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Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172497
Abstract: Metformin, an AMP-activated protein kinase (AMPK) activator, is an oral hypoglycemic drug widely used to treat patients with type 2 diabetes. As AMPK plays a role in the nociceptive processing, investigating the effects induced by…
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Keywords:
activation opioidergic;
metformin;
nociceptive neuropathic;
neuropathic pain ... See more keywords
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Published in 2023 at "Journal of Pharmacy Technology"
DOI: 10.1177/87551225221139699
Abstract: Objectives: To determine the efficacy and safety of commonly prescribed tricyclic antidepressants (TCAs) as analgesics for nociceptive and neuropathic pain in combination with opioids. Data Sources: A comprehensive literature review was conducted with the assistance…
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Keywords:
tricyclic antidepressants;
review;
nociceptive neuropathic;
neuropathic pain ... See more keywords