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Published in 2022 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.2c00121
Abstract: The innate immune receptor nucleotide-binding oligomerization-domain-containing protein 2 (NOD2) represents an important target for the development of structurally defined small molecule immunomodulatory compounds that have great potential to be used either as vaccine adjuvants or…
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Keywords:
nod2 agonists;
single digit;
agonists single;
discovery desmuramylpeptide ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122755
Abstract: NOD2 is an innate immune receptor that constitutes an important target for the development of small molecule immunopotentiators with great potential to be used as vaccine adjuvants. We report here the results of an in…
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Keywords:
nod2 agonists;
immune response;
adjuvant activity;
lipidation nod2 ... See more keywords