Proteostatic stress as a nodal hallmark of replicative aging.
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DOI: 10.1016/j.yexcr.2020.112163
Abstract: Aging is characterized by the progressive decline of physiology at the cell, tissue and organism level, leading to an increased risk of mortality. Proteotoxic stress, mitochondrial dysfunction and genomic instability are considered major universal drivers… read more here.
Keywords: proteostatic stress; nodal hallmark; hallmark replicative; stress ... See more keywords