Suppressing Subcapsular Sinus Macrophages Enhances Transport of Nanovaccines to Lymph Node Follicles for Robust Humoral Immunity.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.0c02240
Abstract: Nanovaccines need to be transported to lymph node follicles to induce humoral immunity and generate neutralized antibody. Here we discovered that subcapsular sinus macrophages play a barrier role to prevent nanovaccines from accessing lymph node… read more here.
Keywords: antibody; subcapsular sinus; lymph node; node follicles ... See more keywords
Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys
Sign Up to like & getrecommendations! Published in 2017 at "Nature Medicine"
DOI: 10.1038/nm.4421
Abstract: Natural killer (NK) cells play an essential role in antiviral immunity, but knowledge of their function in secondary lymphoid organs is incomplete. Lymph node follicles constitute a major viral reservoir during infections with HIV-1 and… read more here.
Keywords: lymph; african green; lymph node; green monkeys ... See more keywords