Transforming growth factor‐&bgr;1 impairs lymph node homing of dendritic cells by downregulating C‐type lectin receptor‐2 expression
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DOI: 10.1016/j.cyto.2018.04.023
Abstract: HighlightsTGF‐&bgr;1 impedes DC migration to regional lymph nodes by reducing CLEC‐2 expression.TGF‐&bgr;1 downregulates CLEC‐2 expression in DCs via c‐Src.c‐Src silencing improves lymph node homing of TGF‐&bgr;1‐treated DCs restoring CLEC‐2 level. &NA; Trafficking of dendritic cells… read more here.
Keywords: bgr; node homing; expression; lymph node ... See more keywords