Sequential Ipilimumab After Chemoradiotherapy in Curative-Intent Treatment of Patients With Node-Positive Cervical Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2019.3857
Abstract: Importance Despite standard chemoradiotherapy (CRT), most women with lymph node (LN)-positive cervical cancer experience disease recurrence. Immunotherapy is being investigated in the up-front treatment setting. Objectives To assess the safety of sequential immunotherapy after CRT… read more here.
Keywords: treatment; node positive; cervical cancer; ipilimumab ... See more keywords
Effect of Elective Internal Mammary Node Irradiation on Disease-Free Survival in Women With Node-Positive Breast Cancer: A Randomized Phase 3 Clinical Trial.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2021.6036
Abstract: Importance The benefit of internal mammary node irradiation (IMNI) for treatment outcomes in node-positive breast cancer is unknown. Objective To investigate whether the inclusion of IMNI in regional nodal irradiation improves disease-free survival (DFS) in… read more here.
Keywords: irradiation; breast; positive breast; node positive ... See more keywords
Diagnostic accuracy of de‐escalated surgical procedure in axilla for node‐positive breast cancer patients treated with neoadjuvant systemic therapy: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4769
Abstract: More initial clinical node‐positive breast cancer patients achieve axillary pathological complete response (ax‐pCR) after neoadjuvant systemic therapy (NST). Restaging axillary status and performing de‐escalated surgical procedures to replace routine axillary lymph nodes dissection (ALND) is… read more here.
Keywords: cancer; node positive; cancer patients; escalated surgical ... See more keywords
Efficacy of adjuvant chemotherapy on overall survival in patients with lymph node‐positive esophageal squamous cell carcinoma: Is oral chemotherapy promising?
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5264
Abstract: The role of adjuvant chemotherapy in patients with pathological lymph node‐positive (pN+) resectable esophageal squamous cell carcinoma (ESCC) remains unclear. We aimed to explore whether adjuvant chemotherapy could improve the overall survival (OS) of patients… read more here.
Keywords: node positive; squamous cell; adjuvant chemotherapy; esophageal squamous ... See more keywords
Phase 2 study of preoperative chemotherapy with nab-paclitaxel and gemcitabine followed by chemoradiation for borderline resectable or node-positive pancreatic ductal adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5971
Abstract: BACKGROUND Neoadjuvant treatment with nab-paclitaxel and gemcitabine for potentially operable pancreatic adenocarcinoma has not been well studied in a prospective interventional trial and could down-stage tumors to achieve negative surgical margins. METHODS A single-arm, open-label… read more here.
Keywords: node positive; nab paclitaxel; borderline resectable; gemcitabine ... See more keywords
Inequalities in the omission of axillary dissection in sentinel lymph node positive patients in the Netherlands: Innovative hospitals are early adopters of a de‐escalating approach
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34400
Abstract: During the last decade completion axillary lymph node dissection (cALND) was gradually omitted in sentinel lymph node positive (SLN+) breast cancer patients. However, adoption varies among hospitals. We analyzed factors associated with the omission of… read more here.
Keywords: node positive; factors associated; hospital; dissection ... See more keywords
The impact of chemotherapy sequence on survival in node‐positive invasive lobular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25492
Abstract: We sought to evaluate the impact of chemotherapy sequence on survival by comparing node‐positive invasive lobular carcinoma (ILC) patients who received neoadjuvant (NACT) and adjuvant (ACT) chemotherapy. read more here.
Keywords: impact chemotherapy; sequence survival; node positive; invasive lobular ... See more keywords
Axillary lymph node dissection in node-positive breast cancer: are ten nodes adequate and when is enough, enough?
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05500-9
Abstract: Purpose National guidelines define adequate axillary lymph node dissections as those yielding ≥ 10 lymph nodes (LNs). We aimed to identify the optimal LN yield among node-positive patients. Methods Using the National Cancer Data Base (2010–2015), we… read more here.
Keywords: lymph; breast cancer; node positive; upfront surgery ... See more keywords
Outcomes and predictive factors for pathological node-positive in radiographically pure-solid, small-sized lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-018-01059-2
Abstract: ObjectivesThe indication of limited resection for radiographically pure-solid, small-sized lung adenocarcinoma is controversial. This study aimed to reveal the long-term outcome of standard surgical treatment and determine the predictive factors for pathological lymph node metastasis… read more here.
Keywords: lung adenocarcinoma; solid small; pure solid; pathological node ... See more keywords
Association between Radical Prostatectomy and Survival in Men with Clinically Node-positive Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "European urology oncology"
DOI: 10.1016/j.euo.2018.09.015
Abstract: Evidence supporting radical prostatectomy (RP) for men with clinically node-positive (cN+) prostate cancer (PC) is limited. In a US national database, we identified 741 men with cN+ nonmetastatic PC diagnosed during 2000-2015 who underwent definitive… read more here.
Keywords: node positive; clinically node; positive prostate; cancer ... See more keywords
Node-positive Nonmetastatic Prostate Cancer: Time to Reconsider Prognostic Staging?
Sign Up to like & getrecommendations! Published in 2019 at "European urology"
DOI: 10.1016/j.eururo.2018.09.017
Abstract: Node-positive nonmetastatic prostate cancer is currently prognosticated as stage IV, despite evidence that a proportion of this patient population can be cured. We provide evidence and request reconsideration of prognostic staging in the next edition… read more here.
Keywords: positive nonmetastatic; node positive; prostate cancer; nonmetastatic prostate ... See more keywords