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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9072-6_8
Abstract: In the central nervous system, the formation of nodes of Ranvier, the short, unmyelinated regions of the axon where voltage-gated sodium channels that mediate saltatory conduction in myelinated nerves are concentrated, is orchestrated by oligodendrocytes,…
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Keywords:
nervous system;
nodes ranvier;
central nervous;
white matter ... See more keywords
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Published in 2022 at "Cell Reports"
DOI: 10.1016/j.celrep.2022.110366
Abstract: Summary The spacing of nodes of Ranvier crucially affects conduction properties along myelinated axons. It is assumed that node position is primarily driven by growing myelin sheaths. Here, we reveal an additional mechanism of node…
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Keywords:
prefigure position;
central nervous;
nodes ranvier;
position ... See more keywords
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Published in 2017 at "Neuroscience Research"
DOI: 10.1016/j.neures.2016.09.010
Abstract: Communication in the central nervous system (CNS) occurs through initiation and propagation of action potentials at excitable domains along axons. Action potentials generated at the axon initial segment (AIS) are regenerated at nodes of Ranvier…
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Keywords:
myelinated cns;
nodes ranvier;
formation disruption;
cns axons ... See more keywords
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Published in 2017 at "Journal of the Peripheral Nervous System"
DOI: 10.1111/jns.12224
Abstract: Paranodal demyelination has been discussed as a potential mechanism of nerve fiber damage in diabetic neuropathy (DNP). Studies on human tissue are limited, as nerve biopsies are invasive and only rarely performed in patients with…
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Keywords:
patients diabetes;
nodes ranvier;
biopsies patients;
skin biopsies ... See more keywords