Genetic inhibition of KV7/M-channels increases the excitability of bronchopulmonary vagal nociceptive nerves
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732751
Abstract: The KV7/M-channel, encoded by Kcnq2-5 genes, generates a “braking” potassium current (IM) and contributes to the regulation of neuronal excitability. We have previously reported that the vagal sensory nerves terminated in the mouse lungs expressed… read more here.
Keywords: kv7; nodose neurons; kcnq2; physiology ... See more keywords
The volume-regulated anion channel (LRRC8) in nodose neurons is sensitive to acidic pH.
Sign Up to like & getrecommendations! Published in 2017 at "JCI insight"
DOI: 10.1172/jci.insight.90632
Abstract: The leucine rich repeat containing protein 8A (LRRC8A), or SWELL1, is an essential component of the volume-regulated anion channel (VRAC) that is activated by cell swelling and ionic strength. We report here for the first… read more here.
Keywords: anion channel; nodose neurons; regulated anion; volume regulated ... See more keywords