IRF4 rs12203592*T/T genotype is associated with nodular melanoma.
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DOI: 10.1097/cmr.0000000000000596
Abstract: Background: Breslow thickness is recognised as one of the most important prognostic tumour features in melanoma. In a recent pooled international study, the interferon regulatory factor-4 (IRF4) intron 4 rs12203592*T single nucleotide polymorphism (SNP) was… read more here.
Keywords: rs12203592; melanoma; irf4 rs12203592; breslow thickness ... See more keywords
BRAF V600 mutation profiling in primary skin nodular melanoma in Indonesia: an analysis using high resolution pyrosequencing
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DOI: 10.1186/s13104-020-05000-w
Abstract: We aimed to investigate the prevalence and type of BRAF V600 mutations and the associations with clinicopathological variables in primary skin nodular melanoma cases in Yogyakarta and Central Java, Indonesia using pyrosequencing. BRAF V600 mutations… read more here.
Keywords: skin nodular; v600; braf v600; nodular melanoma ... See more keywords
Systemic Therapy in Advanced Nodular Melanoma versus Superficial Spreading Melanoma: A Nation-Wide Study of the Dutch Melanoma Treatment Registry
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DOI: 10.3390/cancers14225694
Abstract: Simple Summary Nodular melanoma is associated with a higher locoregional recurrence rate and worse overall survival outcomes. Whether this histologic subtype affects the efficacy of immunotherapy or targeted therapy is unclear. The aim of our… read more here.
Keywords: survival; braf meki; nodular melanoma; melanoma ... See more keywords