Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation.
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DOI: 10.1007/s10858-020-00332-y
Abstract: Protein therapeutics have numerous critical quality attributes (CQA) that must be evaluated to ensure safety and efficacy, including the requirement to adopt and retain the correct three-dimensional fold without forming unintended aggregates. Therefore, the ability… read more here.
Keywords: component analysis; protein therapeutics; principal component; analysis ... See more keywords