Inflammatory and immunometabolic consequences of gut dysfunction in HIV: Parallels with IBD and implications for reservoir persistence and non-AIDS comorbidities
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DOI: 10.1016/j.ebiom.2019.07.027
Abstract: The gastrointestinal mucosa is critical for maintaining the integrity and functions of the gut. Disruption of this barrier is a hallmark and a risk factor for many intestinal and chronic inflammatory diseases. Inflammatory bowel disease… read more here.
Keywords: hiv; parallels ibd; persistence non; non aids ... See more keywords
Sex Differences in Non-AIDS Comorbidities Among People With Human Immunodeficiency Virus
Sign Up to like & getrecommendations! Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab558
Abstract: Abstract Women are grossly underrepresented in human immunodeficiency virus (HIV) clinical and translational research. This is concerning given that people with HIV (PWH) are living longer, and thus accumulating aging-related non-AIDS comorbidities (NACMs); emerging evidence… read more here.
Keywords: sex differences; immunodeficiency virus; aids comorbidities; non aids ... See more keywords
Monitoring Circulating Immune Checkpoint Proteins as Predictors of Non-AIDS Morbid Events in People With HIV Initiating Antiretroviral Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab570
Abstract: Abstract Background Although cell surface immune checkpoint proteins (ICPs) such as PD-1 expressed on T cells are associated with T-cell exhaustion, HIV disease progression, and AIDS events, they have shown limited utility in predicting non-AIDS… read more here.
Keywords: pre event; aids events; immune checkpoint; checkpoint proteins ... See more keywords
Disproportionate Vulnerability to and Unique Aggregation Pattern of Non-AIDS Comorbidities Among Women With HIV in China
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DOI: 10.1093/ofid/ofaf046
Abstract: Abstract Background Whether and how sex plays differential roles in aging-related multimorbidity among people with HIV (PWH) is poorly characterized. Methods We included 2479 PWH and 5376 people without HIV from the baseline assessment of… read more here.
Keywords: aids comorbidities; non aids; unique aggregation; multimorbidity ... See more keywords
2244. Non-AIDS Cancers Contribute to an Increasing Proportion of Deaths in Persons Living with HIV at a Single University-Based Clinic
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DOI: 10.1093/ofid/ofy210.1897
Abstract: Abstract Background Mortality for people living with HIV (PLWH) has drastically decreased since the mid-1990s, and the proportion of deaths due to non-HIV-related conditions has increased. Methods Deceased PLWH were identified within a single academic… read more here.
Keywords: death; aids cancers; proportion deaths; non aids ... See more keywords
Trends & predictors of non-AIDS comorbidities among people living with HIV and receiving antiretroviral therapy in Lebanon
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029162
Abstract: Abstract Combined antiretroviral therapy (cART) increased the life expectancy of people living with Human Immunodeficiency Virus (HIV) (PLHIV) and remarkably reduced the morbidity and mortality associated with HIV infection. Consequently, PLHIV are experiencing non-acquired immunodeficiency… read more here.
Keywords: hiv; hypertension; antiretroviral therapy; people living ... See more keywords
Where is the greatest impact of uncontrolled HIV infection on AIDS and non-AIDS events in HIV?
Sign Up to like & getrecommendations! Published in 2018 at "AIDS"
DOI: 10.1097/qad.0000000000001684
Abstract: Objective: The extent to which controlled and uncontrolled HIV interact with ageing, European region of care and calendar year of follow-up is largely unknown. Method: EuroSIDA participants were followed after 1 January 2001 and grouped… read more here.
Keywords: risk; aids non; uncontrolled hiv; non aids ... See more keywords
Presence of asymptomatic CMV and EBV DNA in blood of persons with HIV starting antiretroviral therapy are associated with non-AIDS clinical events.
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DOI: 10.1097/qad.0000000000002484
Abstract: BACKGROUND Even with antiretroviral therapy (ART), persons with HIV (PWH) experience increased morbidity/mortality. Cytomegalovirus (CMV) and Epstein-Barr-Virus (EBV) co-infections likely exacerbate inflammatory-related diseases. OBJECTIVE To determine if presence of detectable CMV or EBV DNA in… read more here.
Keywords: cmv ebv; ebv; blood; art ... See more keywords
Markers of inflammation and immune dysfunction and non-AIDS cancer risk in adults with HIV.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of acquired immune deficiency syndromes"
DOI: 10.1097/qai.0000000000003667
Abstract: INTRODUCTION We evaluated the association between pre-ART immune dysfunction and inflammation markers and the risk of non-AIDS cancer (NAC) in people with HIV (PWH) after starting ART. METHODS In a case-cohort study nested within CoRIS,… read more here.
Keywords: non aids; risk; dysfunction; immune dysfunction ... See more keywords
Expression of Killer Immunoglobulin Receptor Genes among HIV-Infected Individuals with Non-AIDS Comorbidities
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/1119611
Abstract: Combined antiretroviral therapy (cART) increased the life expectancy of people living with HIV (PLHIV) and remarkably reduced the morbidity and mortality associated with HIV infection. However, non-AIDS associated comorbidities including diabetes, hypertension, hyperlipidemia, and cardiovascular… read more here.
Keywords: killer; hiv infected; infected individuals; aids comorbidities ... See more keywords
Comparison of clinical outcomes of pulmonary nocardiosis between AIDS and non-AIDS patients
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DOI: 10.1186/s12879-024-09519-2
Abstract: Background Nocardia species can affect both immunocompetent and immunocompromised people. Method This retrospective study, from 2009 to 2022, aims to compare the survival analyses of pulmonary nocardiosis in AIDS and non-AIDS patients in northeastern Thailand.… read more here.
Keywords: aids patients; nocardiosis aids; non aids; pulmonary nocardiosis ... See more keywords