Inflammatory and immunometabolic consequences of gut dysfunction in HIV: Parallels with IBD and implications for reservoir persistence and non-AIDS comorbidities
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DOI: 10.1016/j.ebiom.2019.07.027
Abstract: The gastrointestinal mucosa is critical for maintaining the integrity and functions of the gut. Disruption of this barrier is a hallmark and a risk factor for many intestinal and chronic inflammatory diseases. Inflammatory bowel disease… read more here.
Keywords: hiv; parallels ibd; persistence non; non aids ... See more keywords
Sex Differences in Non-AIDS Comorbidities Among People With Human Immunodeficiency Virus
Sign Up to like & getrecommendations! Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab558
Abstract: Abstract Women are grossly underrepresented in human immunodeficiency virus (HIV) clinical and translational research. This is concerning given that people with HIV (PWH) are living longer, and thus accumulating aging-related non-AIDS comorbidities (NACMs); emerging evidence… read more here.
Keywords: sex differences; immunodeficiency virus; aids comorbidities; non aids ... See more keywords
Monitoring Circulating Immune Checkpoint Proteins as Predictors of Non-AIDS Morbid Events in People With HIV Initiating Antiretroviral Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab570
Abstract: Abstract Background Although cell surface immune checkpoint proteins (ICPs) such as PD-1 expressed on T cells are associated with T-cell exhaustion, HIV disease progression, and AIDS events, they have shown limited utility in predicting non-AIDS… read more here.
Keywords: pre event; aids events; immune checkpoint; checkpoint proteins ... See more keywords
2244. Non-AIDS Cancers Contribute to an Increasing Proportion of Deaths in Persons Living with HIV at a Single University-Based Clinic
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1897
Abstract: Abstract Background Mortality for people living with HIV (PLWH) has drastically decreased since the mid-1990s, and the proportion of deaths due to non-HIV-related conditions has increased. Methods Deceased PLWH were identified within a single academic… read more here.
Keywords: death; aids cancers; proportion deaths; non aids ... See more keywords
Trends & predictors of non-AIDS comorbidities among people living with HIV and receiving antiretroviral therapy in Lebanon
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DOI: 10.1097/md.0000000000029162
Abstract: Abstract Combined antiretroviral therapy (cART) increased the life expectancy of people living with Human Immunodeficiency Virus (HIV) (PLHIV) and remarkably reduced the morbidity and mortality associated with HIV infection. Consequently, PLHIV are experiencing non-acquired immunodeficiency… read more here.
Keywords: hiv; hypertension; antiretroviral therapy; people living ... See more keywords
Where is the greatest impact of uncontrolled HIV infection on AIDS and non-AIDS events in HIV?
Sign Up to like & getrecommendations! Published in 2018 at "AIDS"
DOI: 10.1097/qad.0000000000001684
Abstract: Objective: The extent to which controlled and uncontrolled HIV interact with ageing, European region of care and calendar year of follow-up is largely unknown. Method: EuroSIDA participants were followed after 1 January 2001 and grouped… read more here.
Keywords: risk; aids non; uncontrolled hiv; non aids ... See more keywords
Presence of asymptomatic CMV and EBV DNA in blood of persons with HIV starting antiretroviral therapy are associated with non-AIDS clinical events.
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DOI: 10.1097/qad.0000000000002484
Abstract: BACKGROUND Even with antiretroviral therapy (ART), persons with HIV (PWH) experience increased morbidity/mortality. Cytomegalovirus (CMV) and Epstein-Barr-Virus (EBV) co-infections likely exacerbate inflammatory-related diseases. OBJECTIVE To determine if presence of detectable CMV or EBV DNA in… read more here.
Keywords: cmv ebv; ebv; blood; art ... See more keywords
Expression of Killer Immunoglobulin Receptor Genes among HIV-Infected Individuals with Non-AIDS Comorbidities
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/1119611
Abstract: Combined antiretroviral therapy (cART) increased the life expectancy of people living with HIV (PLHIV) and remarkably reduced the morbidity and mortality associated with HIV infection. However, non-AIDS associated comorbidities including diabetes, hypertension, hyperlipidemia, and cardiovascular… read more here.
Keywords: killer; hiv infected; infected individuals; aids comorbidities ... See more keywords
HIV-1-Mediated Acceleration of Oncovirus-Related Non-AIDS-Defining Cancers
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DOI: 10.3390/biomedicines10040768
Abstract: With the advent of combination antiretroviral therapy (cART), overall survival has been improved, and the incidence of acquired immunodeficiency syndrome (AIDS)-defining cancers has also been remarkably reduced. However, non-AIDS-defining cancers among human immunodeficiency virus-1 (HIV-1)-associated… read more here.
Keywords: oncogenic virus; acceleration; defining cancers; aids defining ... See more keywords
Clinical analysis of non-AIDS patients with pulmonary cryptococcosis and the change in their clinical features over 30 years in a tertiary hospital in Beijing, China.
Sign Up to like & getrecommendations! Published in 2022 at "Japanese journal of infectious diseases"
DOI: 10.7883/yoken.jjid.2022.141
Abstract: Over the past few decades, understanding of the clinical features of pulmonary cryptococcosis (PC) has progressed, yet there is a lack of data on the manifestations of PC over time. To investigate the differences in… read more here.
Keywords: time; cryptococcosis; pulmonary cryptococcosis; aids patients ... See more keywords