APC mutations are common in adenomas but infrequent in adenocarcinomas of the non-ampullary duodenum
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-021-01823-x
Abstract: Recent studies highlighted the clinicopathological heterogeneity of non-ampullary duodenal adenomas and adenocarcinomas, but the detailed process of the malignant transformation remains unclear. We analyzed 144 adenomas and 54 adenocarcinomas of the non-ampullary duodenum for immunohistochemical… read more here.
Keywords: adenoma; adenomas adenocarcinomas; non ampullary; mmr ... See more keywords
Case series of non-ampullary duodenal adenomas
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.102730
Abstract: Duodenal adenomas are benign tumours of the duodenum which carry a malignant potential. They are found either sporadically or associated with familial syndromes. Majority of these cases are treated endoscopically but surgical resection is a… read more here.
Keywords: duodenal adenomas; ampullary duodenal; series non; non ampullary ... See more keywords
Non-ampullary–duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinomas
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DOI: 10.1038/modpathol.2016.174
Abstract: Literature on non-ampullary–duodenal carcinomas is limited. We analyzed 47 resected non-ampullary–duodenal carcinomas. Histologically, 78% were tubular-type adenocarcinomas mostly gastro-pancreatobiliary type and only 19% pure intestinal. Immunohistochemistry (n=38) revealed commonness of ‘gastro-pancreatobiliary markers’ (CK7 55, MUC1… read more here.
Keywords: duodenal carcinomas; ampullary duodenal; non ampullary; gastro pancreatobiliary ... See more keywords
Molecular alterations and PD-L1 expression in non-ampullary duodenal adenocarcinoma: Associations among clinicopathological, immunophenotypic and molecular features
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DOI: 10.1038/s41598-019-46167-y
Abstract: Non-ampullary duodenal adenocarcinoma (NADC) is extremely rare. Little is known about its clinicopathological and molecular features or its management. Herein we retrospectively analyzed the cases of 32 NADC patients, focusing on microsatellite instability (MSI), genetic… read more here.
Keywords: ampullary duodenal; non ampullary; molecular features; expression ... See more keywords
Endoscopic therapy of sporadic non-ampullary duodenal adenomas, single centre retrospective analysis
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DOI: 10.1080/00365521.2022.2114810
Abstract: Abstract Introduction Although sporadic non-ampullary duodenal adenomas (SNADA) are rare, with the risk of progression to cancer, they deserve therapy. Endoscopic therapy of SNADA is effective, but with the increased risk of complications, endotherapy should… read more here.
Keywords: adenomas; endoscopic; therapy; sporadic non ... See more keywords
Prognostic factors of non-ampullary duodenal adenocarcinoma
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DOI: 10.1093/jjco/hyy086
Abstract: Background Non-ampullary duodenal adenocarcinoma, excluding carcinoma in the ampulla of Vater, is a rare disease. Although several prognostic factors have been reported, they remain controversial due to the rarity of non-ampullary duodenal adenocarcinoma. The aims… read more here.
Keywords: chemotherapy; ampullary duodenal; prognostic factors; non ampullary ... See more keywords
Risk Factors for Non-Ampullary Duodenal Adenocarcinoma: A Systematic Review.
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DOI: 10.1159/000516561
Abstract: Introduction: An increase in the incidence of duodenal adenocarcinoma has been recently reported. However, little is known about the risk factors for duodenal adenocarcinoma, which are important for screening purposes. We, therefore, aimed to conduct… read more here.
Keywords: risk; ampullary duodenal; non ampullary; risk factors ... See more keywords