A Biomimetic Non-Antibiotic Approach to Eradicate Drug-Resistant Infections.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201806024
Abstract: The chronic infections by pathogenic Pseudomonas aeruginosa (P. aeruginosa) remain to be properly addressed. In particular, for drug-resistant strains, limited medication is available. An in vivo pneumonia model induced by a clinically isolated aminoglycoside resistant… read more here.
Keywords: non antibiotic; drug; drug resistant; approach eradicate ... See more keywords
Non-antibiotic Approaches to Preventing Pediatric UTIs: a Role for D-Mannose, Cranberry, and Probiotics?
Sign Up to like & getrecommendations! Published in 2022 at "Current Urology Reports"
DOI: 10.1007/s11934-022-01094-w
Abstract: While antibiotics have been a staple in the management and even prevention of urinary tract infections (UTIs), it is not without significant consequences due to intolerance and development of antibiotic resistant bacteria. These concerns necessitate… read more here.
Keywords: mannose cranberry; non antibiotic; antibiotic approaches; pediatric utis ... See more keywords
Clinical impact of non-antibiotic recommendations by a multi-disciplinary antimicrobial stewardship team.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2017.01.046
Abstract: INTRODUCTION The multi-disciplinary antimicrobial stewardship team at the study hospital conducts prospective review and feedback on all inpatient orders of piperacillin-tazobactam and carbapenems. In addition, the team provides non-antibiotic recommendations (i.e. additional investigations and infectious… read more here.
Keywords: team; antibiotic recommendations; non antibiotic; antimicrobial stewardship ... See more keywords
Bio-Inspired Self-Adaptive Nanocomposite Array: From Non-antibiotic Antibacterial Actions to Cell Proliferation.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c05980
Abstract: Pathogenic bacterial infection and poor native tissue integration are two major issues encountered by biomaterial implants and devices, which are extremely hard to overcome within a single surface, especially for those without involvement of antibiotics.… read more here.
Keywords: cell proliferation; non antibiotic; surface; antibiotic antibacterial ... See more keywords
Gold nanoparticles bearing a clinically used non-antibiotic drug for combating multi-drug resistant bacteria.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03460c
Abstract: We introduce N-acetyl-L-cysteine (NAC), a clinically used non-antibiotic drug, to the synthesis of antibacterial gold nanoparticles (Au_NAC). Au_NAC shows excellent antibacterial activities against multi-drug resistant (MDR) Gram-negative bacteria and possesses wound healing capabilities. We provide… read more here.
Keywords: gold nanoparticles; non antibiotic; used non; antibiotic drug ... See more keywords
Antibiotic-non-antibiotic combinations for combating extremely drug-resistant Gram-negative 'superbugs'.
Sign Up to like & getrecommendations! Published in 2017 at "Essays in biochemistry"
DOI: 10.1042/ebc20160058
Abstract: The emergence of antimicrobial resistance of Gram-negative pathogens has become a worldwide crisis. The status quo for combating resistance is to employ synergistic combinations of antibiotics. Faced with this fast-approaching post-antibiotic era, it is critical… read more here.
Keywords: drug resistant; gram negative; extremely drug; non antibiotic ... See more keywords
Non-antibiotic therapy for Clostridioides difficile infection: a review
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Clinical Laboratory Sciences"
DOI: 10.1080/10408363.2019.1648377
Abstract: Abstract Clostridioides difficile infection (CDI) is a common infectious disease that is mainly caused by antibiotics. Antibiotic therapy is still the dominant treatment for CDI, although it is accompanied by side effects. Probiotics, fecal microbiota… read more here.
Keywords: non antibiotic; difficile infection; clostridioides difficile; antibiotic therapy ... See more keywords
Non-antibiotic antibacterial peptides and proteins of Escherichia coli: efficacy and potency of bacteriocins
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2020.1816824
Abstract: ABSTRACT Introduction The emergence and spread of antibiotic resistance among pathogenic bacteria drives the search for alternative antimicrobial therapies. Bacteriocins represent a potential alternative to antibiotic treatment. In contrast to antibiotics, bacteriocins are peptides or… read more here.
Keywords: antibiotic antibacterial; peptides proteins; proteins escherichia; non antibiotic ... See more keywords
Combined exposure to non-antibiotic pharmaceutics and antibiotics in the gut synergistically promote the development of multi-drug-resistance in Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2021.2018901
Abstract: ABSTRACT The gut microbiota represents an important reservoir of antibiotic-resistant bacteria (ARB), which poses a significant threat to public health. However, little is known about the emergence of ARB in the gut after the combined… read more here.
Keywords: non antibiotic; antibiotic pharmaceutics; chloramphenicol; resistance ... See more keywords
Non-Antibiotic Approaches to Infection that Preserve the Microbiome in Critically Ill Patients.
Sign Up to like & getrecommendations! Published in 2023 at "Surgical infections"
DOI: 10.1089/sur.2023.020
Abstract: In critically ill patients, the gut microbiota is subjected to various factors including antimicrobial exposure, modified gastrointestinal transit, nutrition support, as well as infection, which may lead to dysbiosis during the intensive care unit and… read more here.
Keywords: ill patients; approaches infection; critically ill; non antibiotic ... See more keywords
Non-antibiotic options for recurrent urinary tract infections in women
Sign Up to like & getrecommendations! Published in 2017 at "British Medical Journal"
DOI: 10.1136/bmj.j5193
Abstract: #### What you need to know Recurrent urinary tract infection in women is a common problem. There is no universally accepted definition, but most clinicians would classify recurrent UTI as being two episodes of infection… read more here.
Keywords: urinary tract; non antibiotic; tract; recurrent uti ... See more keywords