Non-Anticoagulant Heparin Prodrug Loaded Biodegradable and Injectable Thermoresponsive Hydrogels for Enhanced Anti-Metastasis Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800409
Abstract: Metastasis is a pathogenic spread of cancer cells from the primary site to surrounding tissues and distant organs, making it one of the primary challenges for effective cancer treatment and the major cause of cancer… read more here.
Keywords: non anticoagulant; anti metastasis; metastasis; cancer ... See more keywords
Non-anticoagulant effects of low molecular weight heparins in inflammatory disorders: A review.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2016.12.037
Abstract: Low molecular weight heparins (LMWHs) are produced by chemical or enzymatic depolymerization of unfractionated heparin (UFH). Besides their well-known anticoagulant effects, LMWHs have also been reported to exhibit numerous anti-inflammatory properties. Previous studies have, however,… read more here.
Keywords: low molecular; non anticoagulant; molecular weight; weight heparins ... See more keywords
Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients
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DOI: 10.1016/j.ebiom.2020.102969
Abstract: Abstract Coronavirus disease-2019 (COVID-19) is associated with severe inflammation in mainly the lung, and kidney. Reports suggest a beneficial effect of the use of heparin/low molecular weight heparin (LMWH) on mortality in COVID-19. In part,… read more here.
Keywords: covid patients; anticoagulant mechanisms; non anticoagulant; covid ... See more keywords
Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease
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DOI: 10.3390/ph16040584
Abstract: Unfractionated heparin has multiple pharmacological activities beyond anticoagulation. These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low molecular weight and non-anticoagulant heparin derivatives. Anti-inflammatory activities include inhibition of chemokine activity and cytokine… read more here.
Keywords: non anticoagulant; molecular weight; lung disease; heparin ... See more keywords