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Epigenetic Therapy Targets Th1/Th17 Polarization to Reversing Immune Evasion and Treating Leukemia Relapse Post Allogeneic Stem Cell Transplantation in Non-APL AML Patients

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-111671

Abstract: To reverse non-APL AML patients with post-transplantation relapse before hematological relapse(early-stage relapse), we investigated the safety and efficacy of a new epigenetic therapy(DNA methyltransferase inhibitors, Decitabine and histone deacetylase inhibitors, Chidamide, plus Thymalfasin simultaneously). Twenty-four… read more here.

Keywords: epigenetic therapy; relapse; th1 th17; non apl ... See more keywords