A prognostic signature based on three non‐coding RNAs for prediction of the overall survival of glioma patients
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DOI: 10.1002/2211-5463.12602
Abstract: Recent studies have identified certain non‐coding RNAs (ncRNAs) as biomarkers of disease progression. Glioma is the most common primary intracranial cancer, with high mortality. Here, we developed a prognostic signature for prediction of overall survival… read more here.
Keywords: glioma patients; risk; glioma; non coding ... See more keywords
HPV E6/E7‐Induced Acetylation of a Peptide Encoded by a Long Non‐Coding RNA Inhibits Ferroptosis to Promote the Malignancy of Cervical Cancer
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DOI: 10.1002/advs.202414018
Abstract: Although a fraction of functional peptides concealed within long non‐coding RNAs (lncRNAs) is identified, it remains unclear whether lncRNA‐encoded peptides are involved in the malignancy of cervical cancer (CC). Here, a 92‐amino acid peptide is… read more here.
Keywords: non coding; cancer; long non; cervical cancer ... See more keywords
Pathogenic Variants in RNU2-2, a Non-coding Spliceosomal RNA, Cause a Distinctive Developmental and Epileptic Encephalopathy.
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DOI: 10.1002/ana.78071
Abstract: RNU2-2 is a non-coding small nuclear RNA (snRNA) that forms part of the spliceosome. We identified recurrent pathogenic RNU2-2 variants in 4 of 672 (0.6%) patients with developmental and epileptic encephalopathies (DEEs) of unknown cause.… read more here.
Keywords: non coding; developmental epileptic; rnu2 non; pathogenic variants ... See more keywords
The Genomic Code: A Pervasive Encoding/Molding of Chromatin Structures and a Solution of the “Non‐Coding DNA” Mystery
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DOI: 10.1002/bies.201900106
Abstract: Recent investigations have revealed 1) that the isochores of the human genome group into two super‐families characterized by two different long‐range 3D structures, and 2) that these structures, essentially based on the distribution and topology… read more here.
Keywords: pervasive encoding; coding dna; dna; encoding molding ... See more keywords
Non‐coding RNAs in Kawasaki disease: Molecular mechanisms and clinical implications
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DOI: 10.1002/bies.202100256
Abstract: Kawasaki disease (KD) is an acute self‐limiting vasculitis with coronary complications, usually occurring in children. The incidence of KD in children is increasing year by year, mainly in East Asian countries, but relatively stably in… read more here.
Keywords: kawasaki disease; coding rnas; disease; disease molecular ... See more keywords
Unveiling Small Non‐Coding RNA Dynamics During Recombinant Adeno‐Associated Virus Production
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DOI: 10.1002/biot.70092
Abstract: Recombinant adeno‐associated viruses (rAAVs) play a pivotal role in gene therapy, yet the molecular interactions underlying rAAV production in host cells remain incompletely understood. Non‐coding RNAs (ncRNAs), particularly microRNAs (miRNAs) and small nucleolar RNAs (snoRNAs),… read more here.
Keywords: recombinant adeno; adeno associated; non coding; raav ... See more keywords
Long non‐coding RNA MILNR1 retards colorectal cancer growth by inhibiting c‐Myc
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DOI: 10.1002/cac2.12079
Abstract: Dear Editor, Colorectal cancer (CRC) is a prevalent subtype of carcinoma which accounts for about 10% of all cancer diagnosis and is the third leading cause of cancer-related deaths globally [1].However, a great number of… read more here.
Keywords: colorectal cancer; long non; non coding; crc ... See more keywords
New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
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DOI: 10.1002/cac2.12254
Abstract: With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction between long non‐coding RNAs (lncRNAs) and RBPs has also received increasing attention.… read more here.
Keywords: rna binding; long non; coding rnas; binding proteins ... See more keywords
Long non‐coding RNA H19 promotes TDRG1 expression and cisplatin resistance by sequestering miRNA‐106b‐5p in seminoma
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DOI: 10.1002/cam4.1871
Abstract: The role of TDRG1 in tumorigenesis and the progression of seminoma, as well as its role in regulating chemosensitivity of seminoma to cisplatin through the PI3K/Akt/mTOR signaling pathway, has been previously defined. However, the detailed… read more here.
Keywords: cisplatin; long non; tdrg1 expression; non coding ... See more keywords
Long non‐coding small nucleolar RNA host genes in digestive cancers
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DOI: 10.1002/cam4.2622
Abstract: Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs… read more here.
Keywords: coding small; small nucleolar; long non; host genes ... See more keywords
Long non‐coding RNA HULC stimulates the epithelial–mesenchymal transition process and vasculogenic mimicry in human glioblastoma
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DOI: 10.1002/cam4.4083
Abstract: Long non‐coding RNA (lncRNA) HULC (highly upregulated in liver cancer) is considered as an oncogenic factor for various malignant tumors. This study aimed to reveal the role of lncRNA HULC in the malignant behavior of… read more here.
Keywords: mesenchymal transition; hulc; long non; non coding ... See more keywords