Processing and secretion of non-cognate bacteriocins by EnkT, an ABC transporter from a multiple-bacteriocin producer, Enterococcus faecium NKR-5-3.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2020.07.017
Abstract: EnkT is an ATP-binding cassette (ABC) transporter produced by Enterococcus faecium NKR-5-3, which is responsible for the secretion of multiple bacteriocins; enterocins NKR-5-3A, C, D, and Z (Ent53A, C, D, and Z). EnkT has been… read more here.
Keywords: bacteriocin; cognate; abc transporter; non cognate ... See more keywords
Rapid video-based deep learning of cognate versus non-cognate T cell-dendritic cell interactions
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DOI: 10.1038/s41598-021-04286-5
Abstract: Identification of cognate interactions between antigen-specific T cells and dendritic cells (DCs) is essential to understanding immunity and tolerance, and for developing therapies for cancer and autoimmune diseases. Conventional techniques for selecting antigen-specific T cells… read more here.
Keywords: deep learning; non cognate; antigen specific; cell ... See more keywords
Molecular dynamics simulations of cognate and non-cognate AspRS-tRNAAsp complexes
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DOI: 10.1080/07391102.2019.1711188
Abstract: Abstract Aspartyl tRNA synthetase (AspRS), one of the 20 aminoacyl-tRNA synthetases, plays an important role in protein synthesis by catalyzing the aminoacylation reaction and synthesises Aspartyl-tRNA (tRNAAsp). A typical three-dimensional structure of AspRS comprises three… read more here.
Keywords: cognate non; cognate; non cognate; recognition ... See more keywords
Immunogenicity evaluation of viral peptides via non-specific interactions between anti-peptide IgYs and non-cognate peptides.
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DOI: 10.1093/intimm/dxac068
Abstract: Immunogenicity can be evaluated by detecting antibodies induced by an antigen. Presently deployed assays, however, do not consider the negative impacts of antibody poly-specificity, which is well-established at the monoclonal antibody level. Here, we studied… read more here.
Keywords: non cognate; non; immunogenicity evaluation; immunogenicity ... See more keywords
Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1066361
Abstract: Introduction Imprinting broadly neutralizing antibody (bNAb) paratopes by shape complementary protein mimotopes represents a potential alternative for developing vaccine immunogens. This approach, designated as a Non-Cognate Ligand Strategy (NCLS), has recently been used for the… read more here.
Keywords: non cognate; glycan epitopes; hiv; broadly neutralizing ... See more keywords
Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid
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DOI: 10.3390/ijms23158213
Abstract: The human 2-oxoadipate dehydrogenase complex (OADHc) in L-lysine catabolism is involved in the oxidative decarboxylation of 2-oxoadipate (OA) to glutaryl-CoA and NADH (+H+). Genetic findings have linked the DHTKD1 encoding 2-oxoadipate dehydrogenase (E1a), the first… read more here.
Keywords: non cognate; dehydrogenase; functional versatility; oxoadipate dehydrogenase ... See more keywords