Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase
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DOI: 10.1021/acs.jmedchem.1c00535
Abstract: Novel anti-HIV agents are still needed to overcome resistance issues, in particular inhibitors acting against novel viral targets. The ribonuclease H (RNase H) function of the reverse transcriptase (RT) represents a validated and promising target,… read more here.
Keywords: reverse transcriptase; rnase; non diketo; diketo ... See more keywords