Does Risk of Progression from Barrett’s Esophagus to Esophageal Adenocarcinoma Change Based on the Number of Non-dysplastic Endoscopies?
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06483-0
Abstract: There is a large Barrett’s esophagus patient population undergoing endoscopic surveillance. Methods to stratify patients into higher and lower risk groups may enable more varied surveillance intervals for patients with non-dysplastic Barrett’s esophagus that could… read more here.
Keywords: risk; barrett esophagus; esophageal adenocarcinoma; non dysplastic ... See more keywords
Loss of expression of MLH1 in non‐dysplastic crypts is a harbinger of neoplastic progression in sessile serrated adenomas/polyps
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DOI: 10.1111/his.13874
Abstract: Dysplasia in colonic sessile serrated adenomas (SSAs)/sessile serrated polyps often shows loss of MLH1 expression as determined with immunohistochemistry, but the significance of loss of MLH1 expression in non‐dysplastic crypts in these polyps is less… read more here.
Keywords: mlh1; non dysplastic; expression; sessile serrated ... See more keywords
Degree of crypt atypia correlates with progression to high-grade dysplasia/adenocarcinoma in non-dysplastic Barrett's oesophagus.
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DOI: 10.1111/his.14959
Abstract: AIMS Patients with non-dysplastic Barrett's oesophagus (BE) often show a wide range of 'atypical' histological features in the bases of the crypts. However, the significance of crypt atypia has never been evaluated, despite prior studies… read more here.
Keywords: progression; non dysplastic; crypt; dysplasia ... See more keywords
Are Corrupted Non-dysplastic Colonic Crypts the First Histological Event in Experimental Colonic Carcinogenesis?
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DOI: 10.21873/anticanres.11563
Abstract: BACKGROUND The colonic crypts in rats replicate by symmetric fission at the base of the crypts, and proceeds upwards, to generate two separate identical crypts. Recently, anomalous crypts (called corrupted colonic crypts, CCCs) were found… read more here.
Keywords: colonic crypts; cccs; non dysplastic; colonic carcinogenesis ... See more keywords
Progression to cancer in patients with confirmed dysplasia compared to dysplasia downgraded to non-dysplastic metaplasia in Barrett’s esophagus: a retrospective cohort study in Sweden
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DOI: 10.5946/ce.2023.313
Abstract: Background/Aims This study aimed to clarify the risk of progression in patients with non-dysplastic Barrett’s esophagus (NDBE) and patients with confirmed low-grade dysplasia (LGD) and indefinite for dysplasia (IND) after an expert pathologist review of… read more here.
Keywords: cancer; progression; barrett esophagus; dysplasia ... See more keywords