Non-fibril form but not fibril form of human islet amyloid polypeptide 8–20 changes brain functions in mice
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DOI: 10.1371/journal.pone.0296750
Abstract: Whether fibril formation increases or decreases cytotoxicity remains unclear. Aggregation of human islet amyloid polypeptide (hIAPP), a pivotal regulator of glucose homeostasis, impairs the function and viability of pancreatic β cells. Evidence suggests that low-order… read more here.
Keywords: brain functions; non fibril; fibril form; form ... See more keywords