Total Chemical Synthesis of a Non-Fibrillating Human Glycoinsulin.
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DOI: 10.1021/jacs.9b11424
Abstract: Glycosylation is an accepted strategy to improve the therapeutic value of peptide and protein drugs. Insulin and its analogues are life-saving drugs for all type I and 30% of type II diabetic patients. However, they… read more here.
Keywords: insulin; synthesis non; total chemical; non fibrillating ... See more keywords