GCB-type is a favorable prognostic factor in primary CNS diffuse large B-cell lymphomas
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DOI: 10.1016/j.jocn.2020.11.031
Abstract: Primary CNS lymphomas (PCNSLs) are aggressive diffuse large B-cell lymphomas (DLBCLs) limited to the CNS that generally have a poor prognosis. Classification of DLBCL into germinal center B-cell (GCB) and activated B-cell (non-GCB) subtypes has… read more here.
Keywords: gcb; non gcb; cns; gcb type ... See more keywords
Tumor Microenvironment Differs between Germinal Centre B-Cell and Non-Germinal Centre B-Cell like Diffuse Large B-Cell Lymphomas and Has Subtype-Specific Prognostic Impact on Survival
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DOI: 10.1182/blood-2019-129681
Abstract: Introduction Based on the cell of origin, diffuse large B-cell lymphoma (DLBCL) is divided into germinal center B-cell (GCB) and activated B-cell (ABC) like subtypes, which differ in their gene expression profiles and clinical presentation… read more here.
Keywords: non gcb; dlbcls; germinal centre; cell ... See more keywords
Subsets of Follicular Lymphoma (FL) 3B Have Divergent Biological Behavior and Clinical Outcome: Results from the Prospective Multicenter MER and LEO Cohorts
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DOI: 10.1182/blood-2024-194681
Abstract: Background: FL3B is the least common among FL subtypes, accounting for 5-10% of cases. Almost half of FL3B tumors have concurrent diffuse large B cell lymphoma (DLBCL) in the diagnostic tissue biopsy, while FL3B rarely… read more here.
Keywords: fl1 fl3a; dlbcl; fl3b patients; fl3b ... See more keywords
Non-GCB cell of origin leads to inferior outcomes in brazilian diffuse large B-cell lymphoma patients: Bra-DLBCL multicenter registry, retrospective study of over 500 patients
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DOI: 10.1182/blood-2025-6323
Abstract: Introduction Despite the improvement in management of diffuse large B-cell lymphoma (DLBCL) in recent years, the outcome of patients in low and low-middle income countries remains suboptimal. Moreover, clinical presentation, treatment patterns, and long-term outcomes… read more here.
Keywords: progression; study; non gcb; cell ... See more keywords
A super-SILAC based proteomics analysis of diffuse large B-cell lymphoma-NOS patient samples to identify new proteins that discriminate GCB and non-GCB lymphomas
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DOI: 10.1371/journal.pone.0223260
Abstract: Diffuse large B-cell lymphoma—not otherwise specified (DLBCL-NOS) is a large and heterogeneous subgroup of non-Hodgkin lymphoma. DLBCL can be subdivided into germinal centre B-cell like (GCB) and activated B-cell like (ABC or non-GCB) using a… read more here.
Keywords: gcb; lymphoma; non gcb; gcb dlbcl ... See more keywords