Lysine methylation signaling of non-histone proteins in the nucleus
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03142-0
Abstract: Lysine methylation, catalyzed by protein lysine methyltransferases (PKMTs), is a central post-translational modification regulating many signaling pathways. It has direct and indirect effects on chromatin structure and transcription. Accumulating evidence suggests that dysregulation of PKMT… read more here.
Keywords: methylation; lysine methylation; histone proteins; non histone ... See more keywords
DNA damage response and repair pathway modulation by non-histone protein methylation: implications in neurodegeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-019-00538-2
Abstract: Protein post-translational modifications (PTMs) have emerged to be combinatorial, essential mechanisms used by eukaryotic cells to regulate local chromatin structure, diversify and extend their protein functions and dynamically coordinate complex intracellular signalling processes. Most common… read more here.
Keywords: protein; dna damage; methylation; non histone ... See more keywords
Non-Histone Protein Methylation: Biological Significance and Bioengineering Potential.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical biology"
DOI: 10.1021/acschembio.0c00771
Abstract: Protein methylation is a key post-translational modification whose effects on gene expression have been intensively studied over the last two decades. Recently, renewed interest in non-histone protein methylation has gained momentum for its role in… read more here.
Keywords: protein; protein methylation; histone protein; non histone ... See more keywords