Contraception for the Cardiac Patient: a Cardiologist’s Primer
Sign Up to like & getrecommendations! Published in 2020 at "Current Treatment Options in Cardiovascular Medicine"
DOI: 10.1007/s11936-020-00853-7
Abstract: Cardiovascular disease (CVD) is the number one cause of maternal mortality in the USA. There are many cardiac conditions which pose significant risk to maternal health, and these women should be offered options to avoid… read more here.
Keywords: cardiac patient; contraception cardiac; contraception; patient cardiologist ... See more keywords
Neurokinin 3 Receptor Antagonists Compared With Serotonin Norepinephrine Reuptake Inhibitors for Non-Hormonal Treatment of Menopausal Hot Flushes: A Systematic Qualitative Review
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Therapy"
DOI: 10.1007/s12325-021-01900-w
Abstract: Hot flushes/flashes (HFs) or other vasomotor symptoms affect between 45 and 97% of women during menopause. Hormone replacement therapy (HRT) is effective at alleviating menopausal symptoms, but some women cannot or prefer not to take… read more here.
Keywords: menopausal; tolerability; treatment menopausal; hormonal treatment ... See more keywords
Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-21517-5
Abstract: There are no non-hormonal male contraceptives currently on the market despite decades of efforts toward the development of “male pills”. Here, we report that triptonide, a natural compound purified from the Chinese herb Tripterygium Wilfordii… read more here.
Keywords: male contraceptive; reversible non; triptonide reversible; hormonal male ... See more keywords
Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42857-9
Abstract: Gonadotropin Regulated Testicular Helicase (GRTH/DDX25), expressed in the male gonad, is essential for the completion of spermatogenesis. Our early studies revealed a missense mutation (R242H) of GRTH in 5.8% of Japanese patient population with azoospermia.… read more here.
Keywords: interface; non hormonal; site; grth ... See more keywords
Towards a roadmap to advance non-hormonal contraceptive multipurpose prevention technologies: strategic insights from key stakeholders†
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioaa092
Abstract: Abstract The development of non-hormonal contraceptives is critical to increase options for women. In combination with prevention against sexually transmitted infections, they can become an important component of multipurpose prevention technologies (MPTs) which address multiple… read more here.
Keywords: prevention technologies; contraceptive; non hormonal; development ... See more keywords
EP1101 Efffect of a non-hormonal mucoadhesive polycarbophilic vaginal gel on prevalent vaginal symptoms in women who develop vaginal atrophy
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.1143
Abstract: Introduction/Background Gynecological and breast cancer treatments can cause early ovarian failure with vulvovaginal atrophy (VVA) in the medium-long term. Also, external radiotherapy or brachytherapy for cervix, endometrium or digestive cancer has a potential toxicity risk… read more here.
Keywords: atrophy; vaginal gel; cancer; non hormonal ... See more keywords
Non-hormonal replacement therapy regimens: do they have an effect on cardiovascular risk?
Sign Up to like & getrecommendations! Published in 2018 at "Current vascular pharmacology"
DOI: 10.2174/1570161116666180911104942
Abstract: INTRODUCTION Menopause is associated with adverse effects on quality of life of peri-menopausal and post-menopausal women. It also has an impact on the development of cardiovascular disease (CVD). Hormonal treatments are the most effective medications… read more here.
Keywords: replacement therapy; risk; cvd risk; hormonal replacement ... See more keywords