Bridging the gap between rodents and humans: The role of non‐human primates in oxytocin research
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Primatology"
DOI: 10.1002/ajp.22756
Abstract: Oxytocin (OT), a neuropeptide that acts in the brain as a neuromodulator, has been long known to shape maternal physiology and behavior in mammals, however its role in regulating social cognition and behavior in primates… read more here.
Keywords: gap; non human; social cognition; rodents humans ... See more keywords
An 8‐dipole transceive and 24‐loop receive array for non‐human primate head imaging at 10.5 T
Sign Up to like & getrecommendations! Published in 2021 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4472
Abstract: A 32‐channel RF coil was developed for brain imaging of anesthetized non‐human primates (rhesus macaque) at 10.5 T. The coil is composed of an 8‐channel dipole transmit/receive array, close‐fitting 16‐channel loop receive array headcap, and… read more here.
Keywords: array; non human; loop receive; receive array ... See more keywords
Non-human primate models of PD to test novel therapies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1722-y
Abstract: Non-human primate (NHP) models of Parkinson disease show many similarities with the human disease. They are very useful to test novel pharmacotherapies as reviewed here. The various NHP models of this disease are described with… read more here.
Keywords: human primate; non human; test novel; nhp models ... See more keywords
Basal ganglia, movement disorders and deep brain stimulation: advances made through non-human primate research
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1736-5
Abstract: Studies in non-human primates (NHPs) have led to major advances in our understanding of the function of the basal ganglia and of the pathophysiologic mechanisms of hypokinetic movement disorders such as Parkinson’s disease and hyperkinetic… read more here.
Keywords: non human; basal; brain; basal ganglia ... See more keywords
Climate change impacts on potential future ranges of non-human primate species
Sign Up to like & getrecommendations! Published in 2020 at "Climatic Change"
DOI: 10.1007/s10584-020-02776-5
Abstract: Climate change is likely to negatively affect the habitats of non-human primate species. Recent research has identified a near-linear relationship between cumulative CO 2 emissions, and the resulting regional and seasonal temperature increase. Here, we… read more here.
Keywords: human primate; non human; primate; climate change ... See more keywords
Cell-based therapies for the treatment of myocardial infarction: lessons from cardiac regeneration and repair mechanisms in non-human vertebrates
Sign Up to like & getrecommendations! Published in 2018 at "Heart Failure Reviews"
DOI: 10.1007/s10741-018-9750-8
Abstract: Ischemic cardiomyopathy is the cardiovascular condition with the highest impact on the Western population. In mammals (humans included), prolonged ischemia in the ventricular walls causes the death of cardiomyocytes (myocardial infarction, MI). The loss of… read more here.
Keywords: heart; non human; based therapies; myocardial infarction ... See more keywords
Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates
Sign Up to like & getrecommendations! Published in 2021 at "Virologica Sinica"
DOI: 10.1007/s12250-021-00376-w
Abstract: The ongoing coronavirus disease 2019 (COVID-19) pandemic caused more than 96 million infections and over 2 million deaths worldwide so far. However, there is no approved vaccine available for severe acute respiratory syndrome coronavirus 2… read more here.
Keywords: inactivated vaccine; non human; efficacy; sars cov ... See more keywords
Re-evaluation of the 18 non-human protein standards used to create the Empirical Statistical Model for Decoy Library Searching.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113680
Abstract: The Empirical Statistical Model (ESM) for decoy library searching fused the expected amino acid sequence of 18 non-human protein standards to a human decoy library. The ESM assumed a priori the standards were pure such… read more here.
Keywords: protein; empirical statistical; non human; statistical model ... See more keywords
Natural infection by Trypanosoma cruzi in three species of non-human primates in southeast Mexico: A contribution to reservoir knowledge.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105754
Abstract: The mechanisms of infection and dispersion of Trypanosoma cruzi among animals, especially in the sylvatic environment, are still not entirely clear. Therefore, various aspects of the transmission dynamics of this parasite in the sylvatic environment… read more here.
Keywords: natural infection; non human; infection; infection trypanosoma ... See more keywords
Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2019.02.003
Abstract: Fabry disease is an X-linked lysosomal storage disease caused by loss of alpha galactosidase A (α-Gal A) activity and is characterized by progressive accumulation of globotriaosylceramide and its analogs in all cells and tissues. Although… read more here.
Keywords: non human; fabry disease; mice; human primates ... See more keywords
Ribavirin does not potentiate favipiravir antiviral activity against Ebola virus in non-human primates.
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral research"
DOI: 10.1016/j.antiviral.2020.104758
Abstract: BACKGROUND In spite of recurrent and dramatic outbreaks, there are no therapeutics approved against Ebola virus disease. Favipiravir, a RNA polymerase inhibitor active against several RNA viruses, recently demonstrated significant but not complete protection in… read more here.
Keywords: non human; ebola virus; model; bid ... See more keywords