Abstract SP084: Replication stress response defects predict responses to ICT in non-hypermutated tumors
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs20-sp84
Abstract: Immune checkpoint blockade (ICT) has provided robust, durable responses to a subset of patients. Many initial ICT trials were focused on highly mutated cancer types, such as melanoma and lung cancer, largely predicated on the… read more here.
Keywords: response; tumor types; replication; cancer ... See more keywords
Racial/ethnic and sex differences in somatic cancer gene mutations among patients with early-onset colorectal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-22-0764
Abstract: Molecular features underlying colorectal cancer (CRC) disparities remain uncharacterized. Here, we investigated somatic mutation patterns by race/ethnicity and sex among 5,856 non-Hispanic White (NHW), 535 non-Hispanic Black (NHB) and 512 Asian/Pacific Islander (API) CRC patients[2,016… read more here.
Keywords: non hypermutated; early onset; sex; colorectal cancer ... See more keywords