Pellino-2 in non-immune cells: novel interaction partners and intracellular localization.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS letters"
DOI: 10.1002/1873-3468.14212
Abstract: Pellino-2 is an E3 ubiquitin ligase that mediates intracellular signaling in innate immune pathways. Most studies of endogenous Pellino-2 have been performed in macrophages, but none in non-immune cells. Using yeast two-hybrid screening and co-immunoprecipitation,… read more here.
Keywords: interaction partners; pellino; novel interaction; immune cells ... See more keywords
Non-immune-related hypothyroidism and its relationship with excess iodine
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Nutrition"
DOI: 10.1007/s00394-018-1837-4
Abstract: PurposeIn iodine-sufficient areas, autoimmune hypothyroidism has been regarded as the major subtype of hypothyroidism. Non-immune-related hypothyroidism has received little attention because it is considered to be rare. The aim of this study was to evaluate… read more here.
Keywords: hypothyroidism; immune related; excess iodine; non immune ... See more keywords
MafK mediates chromatin remodeling to silence IRF8 expression in non-immune cells in a cell-type specific manner.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.06.005
Abstract: The regulation of gene expression is a result of a complex interplay between chromatin remodeling, transcription factors (TFs) and signaling molecules. Cell differentiation is accompanied by chromatin remodeling of specific loci to permanently silence genes… read more here.
Keywords: mafk; chromatin remodeling; irf8 expression; expression ... See more keywords
Non-immune cells equipped with T cell receptor-like signaling for cancer cell ablation
Sign Up to like & getrecommendations! Published in 2018 at "Nature chemical biology"
DOI: 10.1038/nchembio.2498
Abstract: The ability to engineer custom cell-contact-sensing output devices into human non-immune cells would be useful for extending the applicability of cell-based cancer therapies and avoiding risks associated with engineered immune cells. Here, we have developed… read more here.
Keywords: cell receptor; biology; cancer; immune cells ... See more keywords
Diagnostic yield from prenatal exome sequencing for non‐immune hydrops fetalis: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Genetics"
DOI: 10.1111/cge.14309
Abstract: Non‐immune hydrops fetalis (NIHF) has multiple genetic etiologies diagnosable by exome sequencing (ES). We evaluated the yield of prenatal ES for NIHF, and the contribution of additional clinical findings and history. Systematic review was performed… read more here.
Keywords: non immune; systematic review; immune hydrops; yield prenatal ... See more keywords
Non‐immune hydrops fetalis neonate born to a mother with yellow nail syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Pediatrics International"
DOI: 10.1111/ped.13771
Abstract: rectoscrotal fistula, an extremely rare type of H-type ARM. De Vries and Friedland consider that the H-type fistula is a persistence of the cloacal duct of Reichel. Meanwhile, Stephens and Donnellan propose the two-part septum… read more here.
Keywords: rectum; fistula; type arm; type ... See more keywords
Acute hepatitis B virus infection and severe non-immune haemolytic anaemia: a rare relationship
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-221763
Abstract: The clinical presentation of acute hepatitis B virus (HBV) infection is usually related to the onset of liver failure and damage. Anaemia may occur, but it is only rarely attributed to haemolysis. The authors report… read more here.
Keywords: acute; haemolytic anaemia; infection; non immune ... See more keywords
Dynamics of anti-malarial antibodies in non-immune patients during and after a first and unique Plasmodium falciparum malaria episode
Sign Up to like & getrecommendations! Published in 2020 at "Malaria Journal"
DOI: 10.1186/s12936-020-03300-x
Abstract: Malaria is a major travel medicine issue. Retrospective confirmation of a malaria episode diagnosed in an endemic area can have relevant implications in transfusional medicine in Europe, where blood donors are excluded from donation on… read more here.
Keywords: medicine; malaria episode; serology; anti malarial ... See more keywords
Clinical relevance and therapeutic potential of IL-38 in immune and non-immune-related disorders
Sign Up to like & getrecommendations! Published in 2022 at "European Cytokine Network"
DOI: 10.1684/ecn.2022.0480
Abstract: Interleukin-38 (IL-38) is the most recent member of the IL-1 family that acts as a natural inflammatory inhibitor by binding to cognate receptors, particularly the IL-36 receptor. In vitro, animal and human studies on autoimmune,… read more here.
Keywords: therapeutic potential; clinical relevance; immune non; relevance therapeutic ... See more keywords
Editorial: The Immunomodulatory Properties of Extracellular Vesicles From Pathogens, Immune Cells, and Non-immune Cells
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.03024
Abstract: Intercellular communication is key for immune regulation and extracellular vesicles (EVs) are emerging as important mediators of this process. EVs like exosomes, microvesicles, and apoptotic bodies are membrane-bound vesicles that can be released by both… read more here.
Keywords: extracellular vesicles; immunomodulatory properties; editorial immunomodulatory; properties extracellular ... See more keywords
Trained Immunity Carried by Non-immune Cells
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.03225
Abstract: “Trained immunity” is a term proposed by Netea to describe the ability of an organism to develop an exacerbated immunological response to protect against a second infection independent of the adaptative immunity. This immunological memory… read more here.
Keywords: immune cells; non immune; immunological memory; trained immunity ... See more keywords