Intravitreal Ranibizumab Therapy for Diabetic Macular Edema in Routine Practice: Two-Year Real-Life Data from a Non-interventional, Multicenter Study in Germany
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes Therapy"
DOI: 10.1007/s13300-018-0513-2
Abstract: IntroductionThe prospective, non-interventional OCEAN study examined the use of intravitreal ranibizumab injections for the treatment of diabetic macular oedema (DME) in a real-world setting in Germany.MethodsAdults with DME receiving ≥ 1 ranibizumab (0.5 mg) injections were recruited by… read more here.
Keywords: non interventional; year; diabetic macular; study ... See more keywords
Premature Ejaculation Among Italian Men: Prevalence and Clinical Correlates From an Observational, Non-Interventional, Cross-Sectional, Epidemiological Study (IPER)
Sign Up to like & getrecommendations! Published in 2018 at "Sexual Medicine"
DOI: 10.1016/j.esxm.2018.04.005
Abstract: Introduction There is a great variability in the prevalence of premature ejaculation (PE) worldwide and only few data are available about the Italian population. Aim To determine the prevalence of PE in the adult male… read more here.
Keywords: non interventional; observational non; prevalence; premature ejaculation ... See more keywords
Real-life effectiveness of asthma treatment with a fixed-dose fluticasone/formoterol pressurised metered-dose inhaler - Results from a non-interventional study.
Sign Up to like & getrecommendations! Published in 2017 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2017.08.017
Abstract: OBJECTIVE Prospective, non-interventional study of fixed-dose inhaled corticosteroid (ICS)/long-acting beta2-agonist (LABA) combination therapy with fluticasone propionate/formoterol fumarate (FP/FORM) across a spectrum of community-based patients with asthma in a real-life setting. METHODS In FP/FORM-treated patients aged… read more here.
Keywords: non interventional; treatment; study; interventional study ... See more keywords
Multicenter, non-interventional, double cohort study to assess the safety of alglucosidase alfa and laronidase in real-world home infusion setting
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics and Metabolism"
DOI: 10.1016/j.ymgme.2021.11.319
Abstract: Background: During Coronavirus Disease-19 (COVID-19) pandemic, the way to guarantee the adherence to treatment for patients with lysosomal disorders (LDs) in Italy, was home therapy, allowed by the temporary and exceptional authorization 341/2020 of the… read more here.
Keywords: safety; study; multicenter non; home ... See more keywords
A non-interventional comparative study of the 20:1 combination of cafedrine/theodrenaline versus ephedrine for the treatment of intra-operative arterial hypotension: the ‘HYPOTENS’ study design and rationale
Sign Up to like & getrecommendations! Published in 2018 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2018.1438379
Abstract: Abstract Objective: To compare the effectiveness of 20:1 cafedrine/theodrenaline approved for use in Germany to ephedrine in the restoration of arterial blood pressure and on post-operative outcomes in patients with intra-operative arterial hypotension of any… read more here.
Keywords: non interventional; cafedrine theodrenaline; treatment; study ... See more keywords
Non-interventional observational study broadens positive benefit-risk assessment of an immunomodulating herbal remedy in the common cold
Sign Up to like & getrecommendations! Published in 2019 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2019.1618252
Abstract: Abstract Background: The unique extract of a mixture of Baptisiae tinctoriae radix, Echinaceae pallidae/purpureae radix and Thujae occidentalis herba alleviates the typical symptoms of the common cold and shortens the duration of the disease. Purpose:… read more here.
Keywords: non interventional; herbal remedy; study; common cold ... See more keywords
Efficacy and tolerability of alirocumab in Austrian clinical practice – results of the non-interventional PEARL-AT study
Sign Up to like & getrecommendations! Published in 2020 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2020.1786678
Abstract: Abstract Objective Proprotein convertase subtilisin/kexin type 9 inhibition can be an effective treatment in patients with primary hypercholesterolemia, particularly in cases with concomitant coronary heart disease, peripheral artery occlusive disease or cerebrovascular occlusive disease for… read more here.
Keywords: non interventional; real world; pearl study; study ... See more keywords
PERFUSE: Non-Interventional Cohort Study of Patients Receiving Infliximab Biosimilar SB2: Results in Pediatric Patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000003683
Abstract: Objectives: PERFUSE is a non-interventional study of 1233 patients [inflammatory rheumatic disease, n = 496; inflammatory bowel disease (IBD), n = 737] receiving infliximab (IFX) biosimilar SB2 therapy. This analysis describes response to treatment and… read more here.
Keywords: disease; perfuse non; ibd patients; biosimilar sb2 ... See more keywords
A retrospective non‐interventional study evaluating the pharmacokinetic interactions between cenobamate and clobazam
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia"
DOI: 10.1111/epi.17515
Abstract: Cenobamate is an antiseizure medication (ASM) approved for the treatment of partial‐onset seizures in adults. As both an inductor and an inhibitor of hepatic enzymes, cenobamate affects the metabolism of other ASMs, among which is… read more here.
Keywords: cenobamate clobazam; non interventional; cenobamate; interventional study ... See more keywords
Real‐world evidence from the non‐interventional, prospective, German multicentre PERSIST study of patients with psoriasis after 1 year of treatment with guselkumab
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18218
Abstract: PERSIST was a prospective, non‐interventional, long‐term, German multicentre study of patients with moderate‐to‐severe psoriasis receiving guselkumab, an approved monoclonal antibody that binds to the p19 subunit of interleukin (IL)‐23, in a real‐world setting. read more here.
Keywords: study patients; non interventional; german multicentre; persist ... See more keywords
Use of real-world evidence in postmarketing medicines regulation in the European Union: a systematic assessment of European Medicines Agency referrals 2013–2017
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Open"
DOI: 10.1136/bmjopen-2018-028133
Abstract: Objectives To assess the use, and evaluate the usefulness, of non-interventional studies and routinely collected healthcare data in postmarketing assessments conducted by the European Medicines Agency (EMA). Design We reviewed and systematically assessed all referrals… read more here.
Keywords: non interventional; european medicines; product; evidence ... See more keywords