A DNAzyme sensor based on target-catalyzed hairpin assembly for enzyme-free and non-label single nucleotide polymorphism genotyping.
Sign Up to like & getrecommendations! Published in 2017 at "Talanta"
DOI: 10.1016/j.talanta.2017.03.001
Abstract: Single nucleotide polymorphisms (SNPs) are widely existed in human genome and associated with many diseases. Traditional PCR-based methods for SNP genotyping require protein enzyme, precise control of temperature and removal of resultant products, making the… read more here.
Keywords: enzyme free; dnazyme; single nucleotide; free non ... See more keywords
Target-dependent dual strand extension recycling amplifications for non-label and ultrasensitive sensing of serum microRNA.
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DOI: 10.1016/j.talanta.2019.120651
Abstract: MicroRNAs (miRNAs) are important biomarkers because their abnormal expressions or mutations can usually indicate the development of cancers or other diseases. However, their high family sequence homology and low abundance pose a major challenge for… read more here.
Keywords: extension recycling; strand; dual strand; strand extension ... See more keywords