Should Total Thyroidectomy Be Recommended for Patients with Familial Non-medullary Thyroid Cancer?
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DOI: 10.1007/s00268-020-05473-7
Abstract: It is unknown whether familial non-medullary thyroid cancer (FNMTC) has more aggressive clinical features and a worse prognosis than sporadic non-medullary thyroid cancer (SNMTC). We retrospectively reviewed 2894 patients with differentiated thyroid cancer who underwent… read more here.
Keywords: medullary thyroid; non medullary; thyroid cancer; cancer ... See more keywords
Familial Non-Medullary Thyroid Carcinoma in Pediatric Age: Our Surgical Experience
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DOI: 10.1007/s00268-021-06104-5
Abstract: The purpose of the article was to evaluate the existence of significant clinical, pathological and prognostic differences between familial and sporadic form of pediatric non-medullary thyroid carcinoma, in order to tailor the therapeutic strategy to… read more here.
Keywords: medullary thyroid; non medullary; thyroid carcinoma;
Genetic susceptibility to hereditary non-medullary thyroid cancer
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DOI: 10.1186/s13053-022-00215-3
Abstract: Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the increasing incidence of NMTC in recent years, the familial form of the disease has also become more common than previously reported,… read more here.
Keywords: cancer; medullary thyroid; susceptibility; non medullary ... See more keywords
Susceptibility Genes and Chromosomal Regions Associated With Non-Syndromic Familial Non-Medullary Thyroid Carcinoma: Some Pathogenetic and Diagnostic Keys
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DOI: 10.3389/fendo.2022.829103
Abstract: Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the pathogenesis of sporadic follicular cell derived… read more here.
Keywords: thyroid carcinoma; non medullary; carcinoma; syndromic familial ... See more keywords
Editorial: Non-Syndromic Familial Non-Medullary Thyroid Carcinoma: Clinical and Genetic Update
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DOI: 10.3389/fendo.2022.891903
Abstract: Non-medullary thyroid cancers (NMTCs) originate from the follicular cells of the thyroid gland and account for over 90% of all thyroid cancers. About 3-10% of NMTCs are of familial origin, and familial NMTC (FNMTC) is… read more here.
Keywords: non medullary; non syndromic; medullary thyroid; thyroid ... See more keywords
Genetics of Familial Non-Medullary Thyroid Carcinoma (FNMTC)
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DOI: 10.3390/cancers13092178
Abstract: Simple Summary Non-medullary thyroid carcinoma (NMTC) originates from thyroid follicular epithelial cells and is considered familial when occurs in two or more first-degree relatives of the patient, in the absence of predisposing environmental factors. Familial… read more here.
Keywords: medullary thyroid; genetics; non medullary; thyroid carcinoma ... See more keywords
Genetic Mutations and Variants in the Susceptibility of Familial Non-Medullary Thyroid Cancer
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DOI: 10.3390/genes11111364
Abstract: Thyroid cancer is the most frequent endocrine malignancy with the majority of cases derived from thyroid follicular cells and caused by sporadic mutations. However, when at least two or more first degree relatives present thyroid… read more here.
Keywords: medullary thyroid; non medullary; thyroid cancer; cancer ... See more keywords
Novel Susceptibility Genes Drive Familial Non-Medullary Thyroid Cancer in a Large Consanguineous Kindred
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DOI: 10.3390/ijms24098233
Abstract: Familial non-medullary thyroid cancer (FNMTC) is a well-differentiated thyroid cancer (DTC) of follicular cell origin in two or more first-degree relatives. Patients typically demonstrate an autosomal dominant inheritance pattern with incomplete penetrance. While known genes… read more here.
Keywords: non medullary; familial non; thyroid; thyroid cancer ... See more keywords