THU0022 Analysis of 47 non-mhc ankylosing spondylitis susceptibility loci reveals shared associated variants across caucasians and chinese han
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6219
Abstract: Background Genetic factors play a prominent role in AS pathogenesis. So far over 40 non-MHC Ankylosing Spondylitis(AS) susceptibility loci with genome-wide or suggestive significance have been initially reported in Caucasians, however, lack of association evidence… read more here.
Keywords: non mhc; susceptibility loci; analysis; chinese han ... See more keywords
Genetic susceptibility to multiple sclerosis: interactions between conserved extended haplotypes of the MHC and other susceptibility regions
Sign Up to like & getrecommendations! Published in 2021 at "BMC Medical Genomics"
DOI: 10.1186/s12920-021-01018-6
Abstract: Background To study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes ( CEHs ) of the MHC and three non- MHC “risk-haplotypes” nearby genes EOMES, ZFP36L1, and CLEC16A . Many haplotypes are… read more here.
Keywords: conserved extended; risk; mhc susceptibility; susceptibility ... See more keywords