BRCA1/2 germline testing in non-mucinous epithelial ovarian carcinoma: changing international practice and implications for service provision
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Human Genetics"
DOI: 10.1038/ejhg.2016.138
Abstract: Ovarian carcinoma is the fourth most common cancer for women in Republic of Ireland, with an average of 361 cases per year.1 The association with germline mutations in BRCA1/2 genes in non-mucinous ovarian cancer risk… read more here.
Keywords: brca1 germline; carcinoma; genetics; non mucinous ... See more keywords
Invasive mucinous adenocarcinoma: genetic insights into a lung cancer entity with distinct clinical behavior and genomic features
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DOI: 10.1038/s41379-021-00945-0
Abstract: Invasive mucinous adenocarcinoma (IMA) is defined by the WHO classification as a primary lung adenocarcinoma with tumor cells showing goblet cellor columnar cell-morphology (Fig. 1) with abundant intracytoplasmic mucin. Due to its distinctive clinical features,… read more here.
Keywords: smoking; lung; imas; entity ... See more keywords
Survival difference between mucinous vs. non-mucinous colorectal cancer following cytoreductive surgery and intraperitoneal chemotherapy
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DOI: 10.1080/02656736.2018.1496486
Abstract: Abstract Background: It is believed that the oncologic behavior of mucinous colorectal adenocarcinoma (MC) is different from non-mucinous adenocarcinoma (NMC). The aim of the study is to compare long-term survivals between patients with MC and… read more here.
Keywords: following cytoreductive; intraperitoneal chemotherapy; non mucinous; cytoreductive surgery ... See more keywords
Metagenomic next-generation sequencing as an unconventional approach to warn of tumor cells in a patients with non-mucinous pneumonic-type lung adenocarcinoma: Case report
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DOI: 10.1097/md.0000000000032448
Abstract: Rationale: Pneumonic-type lung cancer (PTLC) is a special type of lung cancer with cough and expectoration as the main clinical symptoms and inflammatory signals as the main imaging manifestations. PTLC can be easily misdiagnosed as… read more here.
Keywords: pneumonic type; lung adenocarcinoma; lung; non mucinous ... See more keywords
Co-analysis of pancreatic cyst fluid carcinoembryonic antigen and glucose with novel cut-off levels better distinguishes between mucinous and non-mucinous neoplastic pancreatic cystic lesions.
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DOI: 10.1177/00045632211053998
Abstract: BACKGROUND Pancreatic cyst fluid analysis plays an important role in distinguishing between mucinous and non-mucinous cyst lesions. We aimed to compare the diagnostic performances of cyst fluid carcinoembryonic antigen (CEA), CA 19-9, and glucose in… read more here.
Keywords: cea; analysis; cut; non mucinous ... See more keywords
The impact of adjuvant chemotherapy on survival in mucinous and non-mucinous rectal adenocarcinoma patients after TME surgery
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DOI: 10.1371/journal.pone.0282211
Abstract: Introduction The value of adjuvant chemotherapy for rectal cancer patients is debated and varies in different subgroups. One such subgroup is mucinous adenocarcinoma (MAC), which is more treatment resistant compared to non-mucinous adenocarcinoma (NMAC). To… read more here.
Keywords: survival; rectal adenocarcinoma; non mucinous; adjuvant chemotherapy ... See more keywords
Is Reflex Germline BRCA1/2 Testing Necessary in Women Diagnosed with Non-Mucinous High-Grade Epithelial Ovarian Cancer Aged 80 Years or Older?
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15030730
Abstract: Simple Summary Approximately 15% of patients diagnosed with high-grade non-mucinous epithelial ovarian cancer (EOC) have a germline BRCA1/2 mutation, although all patients are often able to access germline testing. Importantly, the risk of familial ovarian… read more here.
Keywords: brca1; high grade; germline brca1; germline ... See more keywords