The Neurokinins: Peptidomimetic Ligand Design and Therapeutic Applications.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867325666180913095918
Abstract: The neurokinins are indisputably essential neurotransmitters in numerous patho- and physiological events. Being widely distributed in the central nervous system (CNS) and peripheral tissues, their discovery rapidly promoted them to drugs targets. A necessity for… read more here.
Keywords: ligand design; non peptidic; peptidomimetic ligand; neurokinins peptidomimetic ... See more keywords
Non-Peptidic Small Molecule Components from Cone Snail Venoms
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DOI: 10.3389/fphar.2021.655981
Abstract: Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (>15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against predators and for competitive… read more here.
Keywords: non peptidic; cone snail; small molecule; snail ... See more keywords
Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches
Sign Up to like & getrecommendations! Published in 2018 at "Molecules"
DOI: 10.3390/molecules23123054
Abstract: Chagas disease is one of the primary causes of heart diseases accounting to 50,000 lives annually and is listed as the neglected tropical disease. Because the currently available therapies have greater toxic effects with higher… read more here.
Keywords: discovery non; non peptidic; chagas disease; disease ... See more keywords