Effects of game-based interventions on functional capacity in acutely hospitalised older adults: results of an open-label non-randomised clinical trial.
Sign Up to like & getrecommendations! Published in 2022 at "Age and ageing"
DOI: 10.1093/ageing/afab247
Abstract: BACKGROUND Hospitalisation-associated disability due to reduced physical activity levels and prolonged bedrest episodes are highly prevalent in older adults. OBJECTIVE To assess the effect of gamified interventions on functional capacity in hospitalised older adults. METHODS… read more here.
Keywords: older adults; hospitalised older; functional capacity; non randomised ... See more keywords
Robotic-assisted versus laparoscopic radical prostatectomy for prostate cancer: the first separate systematic review and meta-analysis of randomised controlled trials and non-randomised studies.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgery"
DOI: 10.1097/js9.0000000000000193
Abstract: BACKGROUND Due to the lack of sufficient evidence, it is not clear whether robotic-assisted radical prostatectomy (RARP) or laparoscopic radical prostatectomy (LRP) is better for prostate cancer. We conducted this study by separately pooling and… read more here.
Keywords: meta analysis; randomised studies; non randomised; analysis ... See more keywords
The challenge with systematic reviews of non‐randomised studies in urology
Sign Up to like & getrecommendations! Published in 2018 at "BJU International"
DOI: 10.1111/bju.14105
Abstract: I n this issue, BJU International has made the conscious decision to publish a systematic review (SR) and metaanalysis (MA) by Guo et al. [1] to inform the question of whether patients undergoing nephrouretectomy for… read more here.
Keywords: reviews non; challenge systematic; randomised studies; systematic reviews ... See more keywords
‘Spin’ in urology non‐randomised studies comparing therapeutic interventions: a temporal analysis
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DOI: 10.1111/bju.16342
Abstract: To determine the prevalence of ‘spin’ (i.e., reporting practices that distort the interpretation of results by positively reflecting negative findings or downplaying potential harms) strategies and level of spin in urological observational studies and whether… read more here.
Keywords: urology; randomised studies; spin urology; non randomised ... See more keywords
Factors influencing estimated effectiveness of COVID-19 vaccines in non-randomised studies
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Evidence-Based Medicine"
DOI: 10.1136/bmjebm-2021-111901
Abstract: Non-randomised studies assessing COVID-19 vaccine effectiveness need to consider multiple factors that may generate spurious estimates due to bias or genuinely modify effectiveness. These include pre-existing immunity, vaccination misclassification, exposure differences, testing, disease risk factor… read more here.
Keywords: factors influencing; vaccine effectiveness; influencing estimated; randomised studies ... See more keywords
Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non-randomised pilot study
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open"
DOI: 10.1136/bmjopen-2019-035087
Abstract: Objective Limited evidence suggests integration of pharmacists into the general practice team could improve medicines management for patients, particularly those with multimorbidity and polypharmacy. This study aimed to develop and assess the feasibility of an… read more here.
Keywords: intervention; randomised pilot; study; medication ... See more keywords
Implementing a pharmacogenomic-driven algorithm to guide antiplatelet therapy among Caribbean Hispanics: a non-randomised clinical trial
Sign Up to like & getrecommendations! Published in 2024 at "BMJ Open"
DOI: 10.1136/bmjopen-2024-084119
Abstract: Objectives To assess whether genotype-guided selection of oral antiplatelet drugs using a clinical decision support (CDS) algorithm reduces the rate of major adverse cardiovascular and cerebrovascular events (MACCEs) among Caribbean Hispanic patients, after 6 months.… read more here.
Keywords: among caribbean; trial; risk; antiplatelet ... See more keywords
Evaluating quasi-experimental approaches for estimating epidemiological efficacy of non-randomised field trials: applications in Wolbachia interventions for dengue
Sign Up to like & getrecommendations! Published in 2024 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-024-02291-6
Abstract: Background Wolbachia symbiosis in Aedes aegypti is an emerging biocontrol measure against dengue. However, assessing its real-world efficacy is challenging due to the non-randomised, field-based nature of most intervention studies. This research re-evaluates the spatial–temporal… read more here.
Keywords: wolbachia interventions; quasi experimental; interventions dengue; efficacy ... See more keywords
Nivolumab combined with high dose multisite radiotherapy in previously untreated advanced melanoma (NIRVANA): A non-randomised, open-label, multicenter, phase 2 trial.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.e21505
Abstract: e21505 Background: Outcome of advanced melanoma remains poor for the majority of patients (pts) and new treatment strategies are needed. Preclinical and clinical data suggest a potential increase of the immunotherapy efficacy when combined with… read more here.
Keywords: randomised open; trial; multisite radiotherapy; melanoma ... See more keywords