Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2018.10.004
Abstract: Monoclonal antibodies and derived fragments are used extensively both experimentally and therapeutically. Thorough characterization of such antibodies is necessary and includes assessment of their thermal and storage stabilities. Thus, assessment of the underlying conformational stabilities… read more here.
Keywords: reducing sds; non reducing; antibody; sds page ... See more keywords
Novel glucoamylase-resistant gluco-oligosaccharides with adjacent α-1, 6 branches at the non-reducing end discovered in Japanese rice wine, sake.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116993
Abstract: Sake, a traditional Japanese rice wine, contains various oligosaccharides (Sake oligosaccharides; SAOs) derived from rice starch. We previously found that SAOs reach a high degree of polymerization (DP). In this study, we developed a hydrophilic… read more here.
Keywords: rice wine; rice; non reducing; branches non ... See more keywords
Functionalisation of the non-reducing end of chitin by selective periodate oxidation: A new approach to form complex block polysaccharides and water-soluble chitin-based block polymers.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118193
Abstract: Most polysaccharides used in polysaccharide-based block copolymers are attached to the second block through the reducing end, due to the few and highly polysaccharide specific non-reducing end (NRE) functionalisation methods available. Chitin oligomers, prepared by… read more here.
Keywords: based block; block; non reducing; reducing end ... See more keywords
Using Digestion by IdeS Protease to Improve Quantification of Degradants in Monoclonal Antibodies by Non-Reducing Capillary Gel Electrophoresis.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02630
Abstract: Monoclonal antibodies (mAbs) have become predominant therapeutics by providing highly specific mechanisms of action enabling treatment of complex diseases. However, mAbs themselves are highly complex and require thorough testing and characterization to ensure efficacy and… read more here.
Keywords: capillary gel; reducing cge; gel electrophoresis; non reducing ... See more keywords
Galectin-3 binds selectively to the terminal, non-reducing end of &bgr;(1→4)-galactans, with overall affinity increasing with chain length
Sign Up to like & getrecommendations! Published in 2019 at "Glycobiology"
DOI: 10.1093/glycob/cwy085
Abstract: Galactans are linear polysaccharides of β(1→4)-linked galactose residues. Although they can antagonize galectin function, the nature of their binding to galectins needs to be better defined to develop them as drugs. Here, we investigated interactions… read more here.
Keywords: non reducing; length; reducing end; terminal non ... See more keywords
Characterization of disease-specific chondroitin sulfate non-reducing end accumulation in mucopolysaccharidosis IVA.
Sign Up to like & getrecommendations! Published in 2020 at "Glycobiology"
DOI: 10.1093/glycob/cwz109
Abstract: Morquio syndrome type A, also known as MPS IVA, is a rare autosomal recessive disorder caused by deficiency of N-acetylgalactosamine-6-sulfatase, a lysosomal hydrolase critical in the degradation of keratan sulfate and chondroitin sulfate. The chondroitin… read more here.
Keywords: mps iva; sulfate; non reducing; disease ... See more keywords
Using a non-reducing sugar in the green synthesis of gold and silver nanoparticles by the chemical reduction method
Sign Up to like & getrecommendations! Published in 2018 at "Dyna"
DOI: 10.15446/dyna.v85n206.72136
Abstract: El uso de compuestos quimicos mas biocompatibles y renovables para la obtencion de nanoparticulas metalicas con propiedades y caracteristicas deseadas, se convierte en una ruta alternativa para la reduccion de riesgos ambientales y del grado… read more here.
Keywords: using non; reducing sugar; non reducing; green synthesis ... See more keywords
Safety evaluation of the food enzyme non‐reducing end α‐l‐arabinofuranosidase from the genetically modified Trichoderma reesei strain NZYM‐GV
Sign Up to like & getrecommendations! Published in 2022 at "EFSA Journal"
DOI: 10.2903/j.efsa.2022.7173
Abstract: Abstract The food enzyme non‐reducing end α‐l‐arabinofuranosidase (α‐l‐arabinofuranoside non‐reducing end α‐l‐arabinofuranosidase; EC 3.2.1.55) is produced with the genetically modified Trichoderma reesei strain NZYM‐GV by Novozymes A/S. The genetic modifications do not give rise to safety… read more here.
Keywords: non reducing; safety; food; end arabinofuranosidase ... See more keywords