Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102555
Abstract: Summary Glycogen synthase kinase-3 (GSK-3) is a positive regulator of PD-1 expression in CD8+ T cells and GSK-3 inhibition enhances T cell function and is effective in the control of tumor growth. GSK-3 has two… read more here.
Keywords: non redundant; gsk gsk; cell mediated; gsk ... See more keywords
Non-redundant functions of EMT transcription factors
Sign Up to like & getrecommendations! Published in 2019 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0196-y
Abstract: Epithelial–mesenchymal transition (EMT) is a crucial embryonic programme that is executed by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and other diseases. However, the causal role of EMT and EMT-TFs in… read more here.
Keywords: non redundant; emt transcription; emt tfs; redundant functions ... See more keywords
Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41116-1
Abstract: Adhesion signaling between epithelial cells and the extracellular matrix plays a critical role in maintaining tissue homeostasis and the response to tissue damage. Focal adhesion kinase (FAK) and its close relative Pyk2 are non-receptor tyrosine… read more here.
Keywords: non redundant; epithelial repair; redundant functions; colitis ... See more keywords
Reasoning about redundant and non-redundant alternative causes of a single outcome: Blocking or enhancement caused by the stronger cause
Sign Up to like & getrecommendations! Published in 2019 at "Quarterly Journal of Experimental Psychology"
DOI: 10.1080/17470218.2017.1338302
Abstract: Perceptions of the effectiveness of a moderate probabilistic cause are influenced by the presence of stronger alternative causes. One important idea is that this influence occurs because the strong cause renders the weaker one statistically… read more here.
Keywords: redundant non; alternative causes; redundant alternative; stronger cause ... See more keywords
Efficient approximations of RNA kinetics landscape using non-redundant sampling
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx269
Abstract: Motivation: Kinetics is key to understand many phenomena involving RNAs, such as co‐transcriptional folding and riboswitches. Exact out‐of‐equilibrium studies induce extreme computational demands, leading state‐of‐the‐art methods to rely on approximated kinetics landscapes, obtained using sampling… read more here.
Keywords: non redundant; kinetics landscapes; efficient approximations; rna kinetics ... See more keywords
On the Optimality of 0–1 Data Placement in Cache Networks
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Communications"
DOI: 10.1109/tcomm.2017.2771377
Abstract: Considering cache enabled networks, optimal content placement minimizing the total cost of communication in such networks is studied, leading to a surprising fundamental 0–1 law for non-redundant cache placement strategies, where the total cache sizes… read more here.
Keywords: non redundant; optimality data; cache; placement ... See more keywords
Non-Redundant OFDM Receiver Windowing for 5G Frames and Beyond
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Vehicular Technology"
DOI: 10.1109/tvt.2019.2953233
Abstract: Contemporary receiver windowed-orthogonal frequency division multiplexing (RW-OFDM) algorithms have limited adjacent channel interference (ACI) rejection capability under high delay spread and small fast Fourier transformation (FFT) sizes. Cyclic prefix (CP) is designed to be longer… read more here.
Keywords: non redundant; ofdm; ofdm receiver; interference ... See more keywords
Abstract 6409: Non-redundant mechanisms of immune resistance to radiotherapy converge on innate immunity
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6409
Abstract: Multiple studies have demonstrated synergy between immune checkpoint blockade (ICB) and radiotherapy (RT) in preclinical murine models; however, randomized trials of RT/ICB have been inconsistent in patients with solid tumors. To better understand this discordance,… read more here.
Keywords: icb; non redundant; cd47; resistance ... See more keywords
Mesenchymal Lineage Heterogeneity Underlies Non-Redundant Functions of Pancreatic Cancer-Associated Fibroblasts.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-21-0601
Abstract: Cancer-associated fibroblast (CAF) heterogeneity is increasingly appreciated, but the origins and functions of distinct CAF subtypes remain poorly understood. The abundant and transcriptionally diverse CAF population in pancreatic ductal adenocarcinoma (PDAC) is thought to arise… read more here.
Keywords: non redundant; cancer associated; redundant functions; cancer ... See more keywords
Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01970
Abstract: The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine receptor 3 (CXCR3). With a prototype function of directing temporal and spatial migration… read more here.
Keywords: cxcr3; non redundant; cxc chemokine; chemokine receptor ... See more keywords
Synthesis of the Inverse Kinematic Model of Non-Redundant Open-Chain Robotic Systems Using Groebner Basis Theory
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10082781
Abstract: One of the most important elements of a robot’s control system is its Inverse Kinematic Model (IKM), which calculates the position and velocity references required by the robot’s actuators to follow a trajectory. The methods… read more here.
Keywords: non redundant; robotic systems; basis; open chain ... See more keywords