Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain.
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DOI: 10.1016/j.bpj.2019.12.025
Abstract: Prions are pathological isoforms of the cellular prion protein that is responsible for transmissible spongiform encephalopathies (TSE). Cellular prion protein interacts with copper, Cu(II), through octarepeat and nonoctarepeat (non-OR) binding sites. The molecular details of… read more here.
Keywords: coordination; prion; copper coordination; prion protein ... See more keywords