Mitochondrial PTP Inhibition Through Cyclophilin D Has no Protection Against Non-Reperfused Myocardial Infarction in Female Rats
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DOI: 10.1016/j.freeradbiomed.2017.10.169
Abstract: Background Opening of mitochondrial permeability transition pores (mPTP) plays a critical role in pathogenesis of myocardial infarction (MI)/ischemia-reperfusion (IR). Inhibition of cyclophilin D (CypD), a major regulator of the mPTP, is mostly used for prevention… read more here.
Keywords: myocardial infarction; inhibition; cypd; reperfusion ... See more keywords
The MRI characteristics of the no-flow region are similar in reperfused and non-reperfused myocardial infarcts: an MRI and histopathology study in swine
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DOI: 10.1186/s41747-017-0001-x
Abstract: BackgroundThe no-flow region (NF) visualised by magnetic resonance imaging (MRI) in myocardial infarction (MI) has been explained as the product of reperfusion-injury-induced microvascular obstruction. However, a similar MRI phenomenon occurs in non-reperfused MI. Accordingly, our… read more here.
Keywords: flow region; histopathology; mri; non reperfused ... See more keywords