From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfx025
Abstract: &NA; Non‐human primates (NHPs) are currently considered to be the non‐rodent species of choice for the preclinical safety assessment of single‐stranded oligonucleotide (SSO) drugs. We evaluated minipigs as a potential alternative to NHPs to test… read more here.
Keywords: assessment single; safety assessment; single stranded; safety ... See more keywords
The use of non-rodent model species in microbiota studies
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DOI: 10.1177/0023677219834593
Abstract: In recent years, tremendous advances have been made in our ability to characterize complex microbial communities such as the gut microbiota, and numerous surveys of the human gut microbiota have identified countless associations between different… read more here.
Keywords: model; model species; non rodent; gut microbiota ... See more keywords