Macrophage inhibitory factor (MIF) gene polymorphisms are associated with disease susceptibility and with circulating MIF levels in active non‐segmental vitiligo in patients from western Mexico
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DOI: 10.1002/mgg3.1416
Abstract: The macrophage migration inhibiting factor (MIF) is a protein that promotes the activation of immune cells and the production of other proinflammatory cytokines such as TNF‐α, IL‐1β, and IFN‐γ, which have proposed to play an… read more here.
Keywords: non segmental; vitiligo; factor mif; western mexico ... See more keywords
Vitiligo: An Update on Pathophysiology and Treatment Options
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DOI: 10.1007/s40257-017-0298-5
Abstract: The pathophysiology of vitiligo is becoming increasingly clarified. In non-segmental vitiligo, early factors include activation of innate immunity, inflammasome activation, oxidative stress, and loss of melanocyte adhesion. Nonetheless, the main mechanism leading to non-segmental vitiligo… read more here.
Keywords: non segmental; treatment; pathophysiology; segmental vitiligo ... See more keywords
Increased systemic and epidermal levels of IL‐17A and IL‐1&bgr; promotes progression of non‐segmental vitiligo
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DOI: 10.1016/j.cyto.2016.12.014
Abstract: BACKGROUND Non‐segmental vitiligo (NSV) results from autoimmune destruction of melanocytes. The altered levels of various cytokines have been proposed in the pathogenesis of vitiligo. However, the exact immune mechanisms have not yet been fully elucidated.… read more here.
Keywords: levels 17a; vitiligo; non segmental; bgr ... See more keywords
Ocular changes of non‐segmental vitiligo: A case‐control study
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DOI: 10.1111/ajd.13909
Abstract: Vitiligo is a skin disorder in which the melanocytes are destroyed. Melanocytes can be destroyed anywhere in the body, compromising the function of the organs where they are found. Melanocytes in the epidermis and the… read more here.
Keywords: vitiligo case; non segmental; changes non; segmental vitiligo ... See more keywords
Effects of age of onset on disease characteristics in non‐segmental vitiligo
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DOI: 10.1111/ijd.13425
Abstract: In patients with vitiligo, the clinical and laboratory features of the disease may vary according to time of onset. This is addressed in the literature by only a few studies with conflicting results. The aim… read more here.
Keywords: non segmental; anti; disease; onset disease ... See more keywords
Genital vitiligo in children: Factors associated with generalized, non‐segmental vitiligo
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DOI: 10.1111/pde.13998
Abstract: It remains uncertain as to whether genital vitiligo of childhood is segmental or a forme fruste of non‐segmental disease. This type of vitiligo is sometimes termed figure‐of‐eight disease due to female predominance and perineal and… read more here.
Keywords: non segmental; vitiligo; genital vitiligo; vitiligo children ... See more keywords
Association Among MIF, IFIH1, and IL6 Gene Polymorphisms and Non-Segmental Vitiligo in a Chinese Han Population
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DOI: 10.2147/ccid.s369418
Abstract: Objective The aim of the present study was to investigate the association of single-nucleotide polymorphisms (SNPs) in the macrophage migration inhibiting factor (MIF), interferon-induced Helicase C domain 1 (IFIH1), interleukin-6 (IL6) genes, circulating levels with… read more here.
Keywords: il6; gene polymorphisms; ifih1; segmental vitiligo ... See more keywords
Exploring the Potential Molecular Mechanism of Sijunzi Decoction in the Treatment of Non-Segmental Vitiligo Based on Network Pharmacology and Molecular Docking
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DOI: 10.2147/ccid.s403732
Abstract: Background Non-segmental vitiligo is a common decolorized skin disease. The purpose of this study was to reveal the active components of Sijunzi decoction (SJZD) and the target genes for the treatment of non-segmental vitiligo. Methods… read more here.
Keywords: target genes; pharmacology; segmental vitiligo; non segmental ... See more keywords
Assessment of CXCL10 Before and After Narrow Band UVB Phototherapy in Non-Segmental Vitiligo Patients
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DOI: 10.4103/ijd.ijd_11_22
Abstract: Background: Vitiligo is a common depigmenting skin disorder characterized by white macules and patches accompanied by local melanocyte loss, caused by autoimmune destruction. Vitiligo is classified into two major forms: segmental vitiligo (SV) and non-segmental… read more here.
Keywords: vitiligo patients; non segmental; dermatology; segmental vitiligo ... See more keywords