The role of Syk/IĸB‐α/NF‐ĸB pathway activation in the reversal effect of BAY 61‐3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan‐induced non‐septic shock
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.12864
Abstract: Spleen tyrosine kinase (Syk), a non‐receptor tyrosine kinase, plays an important role in allergic diseases and inflammation. Syk triggers several intracellular signalling cascades including Toll‐like receptor signalling to activate inflammatory responses following fungal infection but… read more here.
Keywords: inflammation; syk; induced non; hypotension inflammation ... See more keywords
Albumin and fibrinogen kinetics in sepsis: a prospective observational study
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DOI: 10.1186/s13054-021-03860-7
Abstract: Background The measurement of circulating substrate concentrations does not provide information about substrate kinetics. It, therefore, remains unclear if a decrease in plasma concentration of albumin, as seen during critical illness, is a consequence of… read more here.
Keywords: non septic; albumin fibrinogen; septic patients; plasma albumin ... See more keywords
Urinary [TIMP-2] × [IGFBP7] and serum procalcitonin to predict and assess the risk for short-term outcomes in septic and non-septic critically ill patients
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DOI: 10.1186/s13613-020-00665-9
Abstract: Background Biomarkers can play a critical role by facilitating diagnosis and stratification of disease, as well as assessment or prediction of disease severity. Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 product… read more here.
Keywords: risk; aki; igfbp7 pct; timp igfbp7 ... See more keywords
Severe but reversible impaired diaphragm function in septic mechanically ventilated patients
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DOI: 10.1186/s13613-022-01005-9
Abstract: Background Whether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time course of septic and non-septic mechanically ventilated… read more here.
Keywords: diaphragm function; septic patients; non septic; mechanically ventilated ... See more keywords
Procalcitonin levels in preterm newborns: Reference ranges during the first three days of life
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DOI: 10.3389/fped.2022.925788
Abstract: Background Sepsis is one of the most important causes of morbidity and mortality in the neonatal period, especially in preterms. Diagnosis is difficult because of specific signs and symptoms. The diagnostic gold standard is blood… read more here.
Keywords: ranges first; reference ranges; life; non septic ... See more keywords