Molecular recognition-driven supramolecular nanoassembly of a hydrophobic uracil prodrug and hydrophilic cytarabine for precise combination treatment of solid and non-solid tumors.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale horizons"
DOI: 10.1039/d1nh00590a
Abstract: Combination chemotherapy has shown distinct therapeutic advantages over monotherapy in clinical cancer treatment, especially for two chemotherapeutic drugs with different mechanisms of action. However, how to achieve efficient co-delivery of two or more drugs with… read more here.
Keywords: non solid; solid non; molecular recognition; supramolecular nanoassembly ... See more keywords
Abstract S12-02: Risk of morbidity and mortality in COVID-19 patients with cancer
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DOI: 10.1158/1557-3265.covid-19-s12-02
Abstract: Introduction: Morbidity and mortality of cancer patients with COVID-19 have not been examined The goal of thisanalysis was to compare the demographics and clinical characteristics of COVID-19 cancer patients to the rest ofCOVID-19 patients and… read more here.
Keywords: patients cancer; mortality; solid cancers; non solid ... See more keywords
Selinexor and the Selective Inhibition of Nuclear Export: A New Perspective on the Treatment of Sarcomas and Other Solid and Non-Solid Tumors
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13091522
Abstract: Nucleocytoplasmic transport has been found dysregulated in many types of cancer and is often described as a poor prognostic factor. Specifically, Exportin-1 (XPO1) has been found overexpressed in many tumors and has become an attractive… read more here.
Keywords: solid tumors; nuclear export; selinexor selective; non solid ... See more keywords