A case of ischemic colitis in a patient with non transfusion dependent thalassemia (NTDT) infected by SARS-COV-2
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2021.1922558
Abstract: Non transfusion dependent thalassemia (NTDT) are a wide spectrum of genetic diseases characterized by anemia, ineffective erythropoiesis and hemolysis which require blood transfusion supplies only in particular conditions such as pregnancy, infections and trauma. Here… read more here.
Keywords: thalassemia; case; non transfusion; sars cov ... See more keywords
Iron overload status in patients with non-transfusion-dependent thalassemia in China
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Hematology"
DOI: 10.1177/20406207221084639
Abstract: Background: Iron overload is one of the main factors that increase morbidity and mortality in patients with non-transfusion dependent thalassemia (NTDT). Aim: This study aimed at investigating the prevalence and severity of iron overload in… read more here.
Keywords: iron overload; thalassemia; patients non; overload ... See more keywords
B0 Vs. Non-B0 Genotype: Differences in Non-Transfusion-Dependent Thalassemia Patients
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-112553
Abstract: Background: In non transfusion dependent thalassemia (NTDT) the lack of a clear genotype-phenotype relationship complicates the already complex and extensive scenario in clinical practice. Our aim was to detect if the presence of a β°/β°… read more here.
Keywords: homozygous genotype; thalassemia; transfusion dependent; non transfusion ... See more keywords
Profile of Luspatercept in the Treatment of Anemia in Adults with Non-Transfusion-Dependent β-Thalassemia (NTDT): Design, Development and Potential Place in Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s368584
Abstract: Abstract Over the past decade, evidence has been mounting on the detrimental clinical sequelae of untreated anemia in patients with non-transfusion-dependent β-thalassemia (NTDT). There are no pharmacologic agents that are specifically approved for the management… read more here.
Keywords: non transfusion; dependent thalassemia; transfusion dependent; therapy ... See more keywords
Sotatercept, a novel transforming growth factor β ligand trap, improves anemia in β-thalassemia: a phase II, open-label, dose-finding study
Sign Up to like & getrecommendations! Published in 2018 at "Haematologica"
DOI: 10.3324/haematol.2018.198887
Abstract: β-thalassemia, a hereditary blood disorder caused by defective synthesis of hemoglobin β globin chains, leads to ineffective erythropoiesis and chronic anemia that may require blood transfusions. Sotatercept (ACE-011) acts as a ligand trap to inhibit… read more here.
Keywords: thalassemia; transfusion dependent; transfusion; non transfusion ... See more keywords
Hemorheological profiles and chronic inflammation markers in transfusion-dependent and non-transfusion- dependent thalassemia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1108896
Abstract: The rheological properties of blood play an important role in regulating blood flow in micro and macro circulation. In thalassemia syndromes red blood cells exhibit altered hemodynamic properties that facilitate microcirculatory diseases: increased aggregation and… read more here.
Keywords: non transfusion; dependent thalassemia; transfusion dependent; thalassemia ... See more keywords
Non-Transfusion-Dependent Thalassemia: A Panoramic Review
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DOI: 10.3390/medicina58101496
Abstract: Non-transfusion-dependent thalassemia (NTDT) has been considered less severe than its transfusion-dependent variants. The most common forms of NTDT include β-thalassemia intermedia, hemoglobin E/beta thalassemia, and hemoglobin H disease. Patients with NTDT develop several clinical complications,… read more here.
Keywords: non transfusion; dependent thalassemia; transfusion dependent; review ... See more keywords