Halogenated boroxine increases propensity to apoptosis in leukemia (UT‐7) but not non‐tumor cells in vitro
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13522
Abstract: A hallmark of the development of solid and hematological malignancies is the dysregulation of apoptosis, which leads to an imbalance between cell proliferation, cell survival and death. Halogenated boroxine [K2(B3O3F4OH)] (HB) is a derivative of… read more here.
Keywords: apoptosis; tumor cells; non tumor; tumor ... See more keywords
Targeting The Tumor Microenvironment in Lymphomas: Emerging Biological Insights and Therapeutic Strategies
Sign Up to like & getrecommendations! Published in 2022 at "Current Oncology Reports"
DOI: 10.1007/s11912-022-01250-y
Abstract: This review aims to discuss recent advances in elucidating the tumor microenvironment (TME) in B lymphomas and resultant novel therapeutic development. While tumor morphology, immunophenotype, and molecular profile are established factors that predict outcome and… read more here.
Keywords: non tumor; tumor cells; tumor microenvironment; lymphomas ... See more keywords
Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.01.022
Abstract: Glioblastoma (GBM) is the most common malignant brain tumor in adults with a median survival of 14.6months. A contributing factor to GBM aggressiveness is the intratumoral expression of the potently immunosuppressive enzyme, indoleamine 2,3 dioxygenase… read more here.
Keywords: cell ido1; non tumor; tumor cell; cell ... See more keywords
Role of ceRNAs in non-tumor female reproductive diseases
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac200
Abstract: Abstract The molecular mechanism of non-tumor female reproductive diseases is complicated and needs to be further elucidated. Recently, increasing evidence indicates that non-coding RNAs(ncRNAs) which are extremely rich in the female reproductive system are crucial… read more here.
Keywords: role cernas; reproductive diseases; female reproductive; non tumor ... See more keywords
Clusterin expression in non-tumor tissue in patients with resectable hepatocellular carcinoma related with post-resectional survival.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000195
Abstract: BACKGROUND Surgical resection offers an effective treatment for patients with hepatocellular carcinoma (HCC); however, it has high tumor recurrence rate. Clusterin is a highly conserved glycoprotein that enhances cell aggregation in vitro. It is upregulated… read more here.
Keywords: non tumor; tissue; clusterin expression; tumor ... See more keywords
Abstract 3135: Validation of a bioinformatic model for classifying non-tumor variants in a cell-free DNA liquid biopsy assay
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3135
Abstract: Background: Liquid biopsy has been established as a powerful, non-invasive means to profile tumors in and identify clinically relevant variants. However, the presence of clonal hematopoiesis (CH) variants, or biological noise, due to aging or… read more here.
Keywords: validation; tumor variants; non tumor; liquid biopsy ... See more keywords
Abstract A011: Bladder cancerization is linked to epithelial basalization and is reversed by EGF inhibition
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.bladder24-a011
Abstract: Introduction: Epithelial changes can extend beyond the boundaries of an incipient tumor, leading to cancer recurrence even after effective excision of the primary tumor. This ‘field cancerization’ and consequent high recurrence rate is especially pronounced… read more here.
Keywords: non tumor; tumor; tumor urothelium; bladder cancer ... See more keywords
Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0283737
Abstract: Background Choledochal cysts (CC) are congenital bile duct anomalies with 6–30% risk for developing bile duct cancer. However, the molecular mechanisms underlying cancer risk of CC are unknown. We sought to identify the gene expression… read more here.
Keywords: fgfr2 cebpb; liver; non tumor; tumor ... See more keywords
Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Oncotarget"
DOI: 10.18632/oncotarget.28306
Abstract: Metabolomics, defined as the comprehensive identification of all small metabolites in a biological sample, has the power to shed light on phenotypic changes associated with various diseases, including cancer. To discover potential metabolomic biomarkers of… read more here.
Keywords: amino acids; hepatocellular carcinoma; biomarkers hepatocellular; essential amino ... See more keywords
AB038. Establishing a reliable semi-automated segmentation method for assessing chemoradiotherapy effects on the non-tumoral brain.
Sign Up to like & getrecommendations! Published in 2024 at "Chinese clinical oncology"
DOI: 10.21037/cco-24-ab038
Abstract: BACKGROUND Current voxel-based morphometry (VBM) studies of chemoradiotherapy effects on healthy tissues of the glioblastoma multiforme (GBM) brain face a challenge with neuroanatomical distortions (tumor, tumor edema, and resection cavities) and limited comparisons can be… read more here.
Keywords: whole brain; non tumor; tumor; chemoradiotherapy effects ... See more keywords
The Role of Myeloid-derived Suppressor Cells and Non-tumor Cells in the Glioma Microenvironment
Sign Up to like & getrecommendations! Published in 2025 at "Current Gene Therapy"
DOI: 10.2174/0115665232365123250325041507
Abstract: Glioma, the most common primary brain tumor, is associated with a poor prognosis largely due to the immunosuppressive environment it creates, which allows it to evade immune surveillance. A key component of this immunosuppressive system… read more here.
Keywords: non tumor; tumor; tumor cells; glioma microenvironment ... See more keywords