Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis
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DOI: 10.1038/s41598-018-35496-z
Abstract: Critical regulation of bile acid (BA) pool size and composition occurs via an intensive molecular crosstalk between the liver and gut, orchestrated by the combined actions of the nuclear Farnesoid X receptor (FXR) and the… read more here.
Keywords: fibrosis; fgf19; non tumorigenic; bile acid ... See more keywords
Comparison of the Toxicological Effects of Pesticides in Non-Tumorigenic MCF-12A and Tumorigenic MCF-7 Human Breast Cells
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DOI: 10.3390/ijerph19084453
Abstract: Humans are exposed to residues of organophosphate and neonicotinoid pesticides, commonly used in agriculture. Children are particularly vulnerable and, among possible adverse outcomes, the increased incidence of premature mammary gland development (thelarche) has raised concern.… read more here.
Keywords: non tumorigenic; mcf; toxicological effects; tumorigenic mcf ... See more keywords
Glyphosate and Aminomethylphosphonic Acid (AMPA) Modulate Glutathione S-Transferase in Non-Tumorigenic Prostate Cells
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DOI: 10.3390/ijms24076323
Abstract: Glyphosate (GLY) was developed in the early 1970s and has become the most used broad-spectrum herbicide in the world so far. Its main metabolite is aminomethylphosphonic acid (AMPA), and the accumulation of GLY and its… read more here.
Keywords: non tumorigenic; cell; prostate; aminomethylphosphonic acid ... See more keywords