Clinical application of bone morphogenetic proteins for bone healing: a systematic review
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DOI: 10.1007/s00264-017-3471-9
Abstract: PurposeThis paper documents the existing evidence on bone morphogenetic proteins (BMPs) use for the treatment of bone fractures, non-union, and osteonecrosis, through a review of the clinical literature, underlying potential and limitations in terms of… read more here.
Keywords: morphogenetic proteins; systematic review; bone healing; non union ... See more keywords
Leeds-Genoa Non-Union Index: a clinical tool for asessing the need for early intervention after long bone fracture fixation
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DOI: 10.1007/s00264-019-04376-0
Abstract: Aim of the study The aim of this case–control study was to develop a clinical decision rule to support assessment of the risk of long-bone non-union and plan for appropriate early intervention. Methods Two hundred… read more here.
Keywords: index; fracture; risk factors; non union ... See more keywords
Risk factors associated with non-union after triple pelvic osteotomy (Toennis and Kalchschmidt technique): a case–control study and review of the literature
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DOI: 10.1007/s00402-018-3060-4
Abstract: IntroductionDysplasia of the hip is a well known cause of secondary osteoarthritis of the hip. The triple pelvic osteotomy (TPO), according to the technique described by Toennis and Kalchschmidt, is a well established procedure to… read more here.
Keywords: triple pelvic; control; non union; pelvic osteotomy ... See more keywords
Synergistic use of biomaterials and licensed therapeutics to manipulate bone remodelling and promote non-union fracture repair.
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DOI: 10.1016/j.addr.2020.10.011
Abstract: Disrupted bone metabolism can lead to delayed fracture healing or non-union, often requiring intervention to correct. Although the current clinical gold standard bone graft implants and commercial bone graft substitutes are effective, they possess inherent… read more here.
Keywords: fracture; licensed therapeutics; non union; bone ... See more keywords
Genetic determinants of fracture non-union: A systematic review from the literature.
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DOI: 10.1016/j.gene.2020.144766
Abstract: Approximately 10-15% of fracture patients suffer impaired healing, which is either delayed or even results in non-union. We performed a Systematic Review, aiming to examine the types and frequency of specific genetic abnormalities in patients… read more here.
Keywords: non union; union; systematic review; fracture non ... See more keywords
Lambeau osseux interosseux postérieur pour l’avant-bras pédiatrique
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DOI: 10.1016/j.hansur.2018.10.115
Abstract: Posterior interosseous bone flap (PIBF) is a reliable vascularised bone graft in adults for treatment of forearm and elbow difficult nonunions. In our best knowledge there is no published experiments on this technique in children.… read more here.
Keywords: physis; radius; treatment; distal radius ... See more keywords
Microvascular reconstruction of the mandible with medial femoral condylar flap for treatment of mandibular non-union.
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DOI: 10.1016/j.ijom.2021.05.007
Abstract: Mandibular non-union occurs in 2-9% after open reduction and internal fixation of a mandibular fracture (trauma surgery, orthognathic cases, access osteotomy for oncological purposes). The medial femoral condyle (MFC) has emerged more recently as one… read more here.
Keywords: reconstruction; flap; treatment; mandibular non ... See more keywords
Modified Masquelet technique using allogeneic umbilical cord-derived mesenchymal stem cells for infected non-union femoral shaft fracture with a 12 cm bone defect: A case report
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DOI: 10.1016/j.ijscr.2017.03.002
Abstract: Highlights • A case of infected non-union fracture with critical-sized bone defect.• Modified Masquelet technique was used to overcome the defect.• The addition of allogenic UC-MSCs, BMP-2 and hydroxyapatite encourages healing.• This technique may serve… read more here.
Keywords: technique; bone defect; case; non union ... See more keywords
Autologous tendon graft for non-union distal clavicle fracture in a patient with chronic kidney disease
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DOI: 10.1016/j.ijscr.2020.10.106
Abstract: Highlights • Autologous tendon grafting in distal clavicle non-union fracture can be an option of treatment.• In a poor environment with impaired bone healing, biological support, such as autologous tendon graft, to maintain fracture reduction… read more here.
Keywords: distal clavicle; fracture; graft; autologous tendon ... See more keywords
Validation of a long bone fracture non-union healing score after treatment with mesenchymal stromal cells combined to biomaterials.
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DOI: 10.1016/j.injury.2020.02.030
Abstract: The available scores to clinically evaluate fracture consolidation encounter difficulties to interpret progression towards consolidation in long-bone non-union, particularly when incorporating biomaterials in the surgical treatment. The aims of this study were to validate the… read more here.
Keywords: long bone; consolidation; bone healing; non union ... See more keywords
Outcome of revision surgery for bisphosphonate related subtrochanteric fracture non-union following failed intramedullary nailing.
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DOI: 10.1016/j.injury.2020.09.051
Abstract: BACKGROUND Bisphosphonates use is a recognised cause of atypical femur fractures. Intramedullary nailing is the first line of treatment for these fractures, but failure is a common problem due to altered biology, resulting in a… read more here.
Keywords: bisphosphonate; revision surgery; union; non union ... See more keywords