Unexpected UVR and non-UVR mutation burden in some acral and cutaneous melanomas
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DOI: 10.1038/labinvest.2016.143
Abstract: Ultraviolet radiation (UVR) mutagenesis causes nearly all cutaneous melanomas, however, since UVR signatures are largely absent in acral melanoma, as well as melanoma in sun-protected sites, the cause of these melanomas is unknown. Whole-genome sequencing… read more here.
Keywords: melanomas; non uvr; mutation burden; cutaneous melanomas ... See more keywords