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   Articles with "noncanonical autophagy" as a keyword



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A noncanonical autophagy is involved in the transfer of Plasmodium-microvesicles to astrocytes.

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recommendations! Published in 2021 at "Autophagy"

DOI: 10.1080/15548627.2021.1993704

Abstract: Cerebral malaria is a neuroinflammatory disease induced by P. falciparum infection. In animal models, the neuro-pathophysiology of cerebral malaria results from the sequestration of infected red blood cells (iRBCs) in microvessels that promotes the activation… read more here.

Keywords: pba mvs; involved transfer; noncanonical autophagy; cerebral malaria ... See more keywords
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Shear stress induces noncanonical autophagy in intestinal epithelial monolayers

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recommendations! Published in 2017 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e17-01-0021

Abstract: Shear stress applied on the apical side of polarizing intestinal cells induces vacuole formation via the autophagy machinery. This response is relayed through apical microvilli that act as mechanosensors linking the physical environment to the… read more here.

Keywords: induces noncanonical; intestinal epithelial; autophagy intestinal; shear stress ... See more keywords

Unveiling the Noncanonical Autophagy-Independent Role of ATG7 and ATG9B in Head and Neck Squamous Cell Carcinoma (HNSCC)

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recommendations! Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/9253938

Abstract: The role of autophagy in cancer remains elusive, and nontargeted autophagy inhibitors have limited therapeutic effects in HNSCC. Here, we systematically analyzed the correlation of autophagy-related genes in HNSCC through TCGA and single-cell sequencing data… read more here.

Keywords: cell; noncanonical autophagy; role; autophagy independent ... See more keywords
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&agr;v Integrins regulate germinal center B cell responses through noncanonical autophagy

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recommendations! Published in 2018 at "Journal of Clinical Investigation"

DOI: 10.1172/jci99597

Abstract: Germinal centers (GCs) are major sites of clonal B cell expansion and generation of long-lived, high-affinity antibody responses to pathogens. Signaling through TLRs on B cells promotes many aspects of GC B cell responses, including… read more here.

Keywords: cell responses; agr integrins; noncanonical autophagy; cell ... See more keywords

Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy.

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recommendations! Published in 2020 at "Journal of cell science"

DOI: 10.1242/jcs.252015

Abstract: Autophagy plays an essential role in the defence against many microbial pathogens as a regulator of both innate and adaptive immunity. Among some pathogens, sophisticated mechanisms have evolved that promote their ability to evade or… read more here.

Keywords: vibrio cholerae; maka; cytotoxin maka; autophagy ... See more keywords