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   Articles with "noncanonical wnt" as a keyword



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Battle in stem cell niches: Canonical versus noncanonical Wnt signaling

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recommendations! Published in 2018 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.2ce1117-453rr

Abstract: Stem cell niches are specialized microenvironments that regulate stem cell-specific properties, including multipotentiality, self-renewal, and quiescence. Wnt signaling in stem cell niches plays a critical role in regulating stem cells from multiple tissues, including embryonic,… read more here.

Keywords: noncanonical wnt; wnt signaling; wnt; stem cell ... See more keywords
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HERES, a lncRNA that regulates canonical and noncanonical Wnt signaling pathways via interaction with EZH2

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recommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1912126116

Abstract: Significance Aberrant lncRNA expression is responsible for cancer progression and metastasis, positioning lncRNAs not only as biomarkers but also as promising therapeutic targets for curing cancer. A number of lncRNAs have been reported in ESCC… read more here.

Keywords: signaling pathways; wnt signaling; canonical noncanonical; noncanonical wnt ... See more keywords
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Noncanonical Wnt as a prognostic marker in prostate cancer: “you can’t always get what you Wnt”

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recommendations! Published in 2019 at "Expert Review of Molecular Diagnostics"

DOI: 10.1080/14737159.2020.1702522

Abstract: ABSTRACT Introduction: Wnt signaling is important for normal development, cell proliferation, and cell differentiation. However, aberrations in the pathway can lead to tumorigenesis and cancer progression. Recent genome-wide studies have demonstrated the frequent occurrence of… read more here.

Keywords: cancer; noncanonical wnt; wnt pathway; prostate cancer ... See more keywords
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Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling

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recommendations! Published in 2022 at "Journal of Cell Science"

DOI: 10.1242/jcs.259547

Abstract: ABSTRACT Dishevelled is a cytoplasmic hub that transduces Wnt signals to cytoplasmic effectors, which can be broadly characterised as canonical (β-catenin dependent) and noncanonical, to specify cell fates and behaviours during development. To transduce canonical… read more here.

Keywords: noncanonical wnt; domain; pdz domain; polarity ... See more keywords
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Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation

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recommendations! Published in 2023 at "EMBO reports"

DOI: 10.15252/embr.202254895

Abstract: Colon tumors of the mesenchymal subtype have the lowest overall survival. Snail1 is essential for the acquisition of this phenotype, characterized by increased tumor stemness and invasion, and high resistance to chemotherapy. Here, we find… read more here.

Keywords: snail1; tumor; colon tumor; noncanonical wnt ... See more keywords