Noncatalytic destruction of 5-acylcomanic acid esters in the presence of 2-methylindoles as a new method for the synthesis of indolylchalcones
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DOI: 10.1007/s10593-017-2147-0
Abstract: Ethyl esters of 5-acylcomanic acids reacted with 2-methylindoles in 3:1 propanol–water mixture in the absence of catalyst, resulting in pyrone ring opening and destruction of the molecular framework and leading to trans-indolylchalcones in 52–70% yields. read more here.
Keywords: noncatalytic destruction; destruction acylcomanic; acid esters; destruction ... See more keywords